MNM-1A-3 マイクロ流体力を用いたベシクルサイズ分離デバイス(セッション 1A マイクロ・ナノスケールバイオ計測と医用応用)

概要

論文の詳細を見る
Controlling vesicle movements is the key factor for applying vesicles as careers of drug deliver, and numbers of researches on this field have been done. For example, some group use the method to tether vesicle to 2D supported lipid bilayer membranes by using oligonucleotide hybridization on the membrane surface. Once tethered, the vesicles can diffuse laterally on the supported membrane surface as lipids do in fluid supported membrane. Taking advantage of this method, the previous research controlled vesicle movements two dimensionally using electric field applied to the bilayer surface. In our research, we propose a device for size separation of vesicles by controlling the motion of tethered vesicles on 2D supported lipid bilayer using microchannel flow.
一般社団法人日本機械学会の論文
2010-10-12