マイクロ針を用いた血糖値計測用シリンジ復動型自動採血デバイスの開発(機械力学,計測,自動制御)

概要

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In this study, a portable type HMS (Health Monitoring System) device for the blood glucose level measurement is newly developed. It has features 1) puncturing a blood vessel by using a minimally invasive micro-needle, 2) extracting and transferring human blood and 3) measuring blood glucose level. This miniature SMBG (Self-Monitoring of Blood Glucose) device employs a syringe reciprocal blood extraction system equipped with an electro-mechanical control unit for accurate and steady operations. The device consists of a disposable syringe unit, a non-disposable body unit, and a glucose enzyme sensor. The experimental results using our miniature SMBG device was confirmed to output more than 90% volumetric efficiency under the driving speed of the piston, 1.0mm/s. In this condition, the extraction flow rates for the inner diameters of the micro-needle 80, 100 and 115μm are 3.6, 3.9 and 3.9μl/s. Further, the blood sugar level was measured successfully by using the glucose enzyme sensor.
2010-02-25