S0201-3-1 BaTiO_3圧電薄膜が骨髄細胞に及ぼす影響(マイクロ・ナノバイオメカニクス:細胞生物学への接近(3)界面と接着)

概要

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It is considered that a piezoelectric thin film coating on implant surface could accelerate cell activity and bone formation. Purpose of this study is to develop a surface treatment to enhance osseointegration for fixation of implants. Alumina ceramic plates and titanium alloy plates with and without a barium titanate (BaTiO_3) thin film coating were prepared as specimen. BaTiO_3 is a lead-free piezoelectric material. The biocompatibility of these specimens was evaluated by cytotoxicity assay with rat bone marrow cells. Effects of BaTiO_3 thin film coating on differentiation of bone marrow cells to osteoblast cells were also evaluated. As a result, it was suggested that BaTiO_3 thin film coating could be safely used for implant materials as a novel surface treatment.
2009-09-12