Acquired Hemophilia First Manifesting as Life-Threatening Intracranial Hemorrhage
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概要
- 論文の詳細を見る
A 74-year-old man presented with life-threatening intracranial hemorrhage and prolonged activated partial thromboplastin time (APTT). The massive subdural hematoma was removed, but multiple intracranial hemorrhages occurred despite the administration of factor VIII and factor IX concentrates. Subdural hematoma, intracerebral hemorrhage in the left temporal lobe, and thalamic hemorrhage subsequently occurred with further prolongation of APTT. He died of enlargement of the thalamic hemorrhage. Acquired hemophilia was diagnosed caused by factor VIII inhibitor. Acquired hemophilia may cause life-threatening hemorrhage, and should be considered in patients with intracranial hemorrhages associated with unexplained prolongation of APTT.
- 社団法人日本脳神経外科学会の論文
- 2009-02-15
著者
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MATSUMURA Akira
Department of Neurosurgery, Graduate School of Comprehensive Human Sciences, University of Tsukuba
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Matsumura A
茨城県立中央病院 総合診療科
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Noguchi Shozo
Department Of Neurosurgery Kitaibaraki Municipal General Hospital
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Noguchi Shozo
Department Of Neurosurgery Ibaraki Prefectural Central Hospital
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SATO Masayuki
Department of Physics, Science University of Tokyo Kagurazaka
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Matsumura Akira
Department Of Neurosurgery Graduate School Of Comprehensive Human Sciences University Of Tsukuba
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Mashiko Ryota
Department Of Neurosurgery Kitaibaraki Municipal General Hospital
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Mashiko Ryota
Department Of Neurosurgery Institute Of Clinical Medicine
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Yamamoto Tetsuya
Department Of Chemical Engineering Graduate School Of Engineering Hiroshima University
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Matsumura Akira
Department Of Gastroenterology Dokkyo Medical University
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Sato Masayuki
Department Of Neurosurgery Graduate School Of Comprehensive Human Sciences University Of Tsukuba
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Yamamoto Tetsuya
Department Of Astronomy School Of Science The University Of Tokyo
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Sato Masayuki
Department Of Biological And Chemical Engineering Gunma University
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Yamamoto Tetsuya
Department Of Neurosurgery Doctoral Program In Functional And Regulatory Medical Science Graduate Sc
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MATSUMURA Akira
Department of Electronic Science and Engineering, Faculty of Engineering, Kyoto University
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