Antitumor and Immunostimulatory Effects of Residual Powder from Barley-Shochu Distillation Remnants
スポンサーリンク
概要
- 論文の詳細を見る
The development of effective utilization methods of Shochu distillation remnants is desirable from the viewpoint of environmental protection and biomass. In this study, we examined inhibitory effects of the powder (barley-powder) obtained from the barley-Shochu distillation remnants on the various tumor cells in vitro and immunostimulation effect in vivo. Remarkable inhibitory effects on the growth of human lung tumor cells along with the induction of apoptosis were obtained for barley-powder in vitro. On the other hand, the barley-powder induced the production of serum Interferon (IFN)t-y for normal rats in vivo, and increased natural killer (NK) activity. Furthermore, the barley-powder showed no acute toxicity in the tail vein administration to normal rats. It was found that the barley-powder had not only an antitumor effect but also an immunostimulation effect for the first time.
- 公益社団法人日本薬学会の論文
- 2008-06-01
著者
-
GOTO Koichi
Division of Thoracic Oncology, National Cancer Center Hospital East
-
Goto K
Graduate Course Of Applied Life Science Sojo University
-
Goto Koichi
Division Of Cardiology Sakurabashi Watanabe Hospital
-
上岡 龍一
熊本工業大学工学部 応用化学科
-
上岡 龍一
Division Of Applied Life Science Graduate School Of Engineering Sojo University
-
上岡 龍一
熊本工業大学工学部工業化学科
-
UEOKA Ryuichi
Division of Applied Chemistry, Graduate School of Kumamoto Institute of Technology
-
TANOUE Osamu
Division of Applied Chemistry, Graduate School of Kumamoto Institute of Technology
-
ICHIHARA Hideaki
Division of Applied Life Science, Graduate School of Engineering, Sojo University
-
Funamoto Kouta
Division of Applied Life Science, Graduate School of Engineering, Sojo University
-
Komizu Yuji
Division of Applied Life Science, Graduate School of Engineering, Sojo University
-
Komizu Yuji
Division Of Applied Life Science Graduate School Of Engineering Sojo University
-
Tanoue Osamu
Sojo University
-
Ueoka Ryuichi
Sojo University
-
Funamoto Kouta
Division Of Applied Life Science Graduate School Of Engineering Sojo University
-
Goto K
Div. Of Applied Life Sci. Graduate School Of Engineering Sojo Univ.
-
Goto Koichi
Division of Applied Life Science, Graduate School of Engineering, Sojo University
関連論文
- Three novel single nucleotide polymorphisms in UGT1A10
- 8-スルホンアミドキノリン系抽出剤の液液界面吸着現象に関する定量的構造物性相関
- ハイブリッドリポソームを用いた大腸がんの肝転移抑制に関する基礎研究
- コトンラット胃腫瘍由来腹水性がん細胞株に対するハイブリッドリポソームの増殖抑制効果
- 糖含有三成分系ハイブリッドリポソームの物性と制がん効果に関する基礎研究
- 焼酎粕からの抗腫瘍性物質の生産
- ハイブリッドリポソーム単独投与によるマウス神経芽腫肝転移抑制効果
- アポトーシス誘導ハイブリッドリポソームによるがん治療
- 副作用のないがん治療への挑戦--ハイブリッドリポソーム・生理活性物質 (特集 次世代バイオテクノロジーの展開)
- アポトーシス誘導リポソームのがん治療
- 糖尿病モデルラットを用いたインシュリン含有複合脂質膜の経口治療に関する基礎的研究
- リポソームによるがん治療と診断 (特集 先端治療システム開発の最前線)
- 1C15-5 キノコ抽出物の培養がん細胞に対する増殖抑制効果
- 抗がん剤を含まないハイブリッド型リポソームのみによるin Vivoでのがん化学療法
- アポトーシス誘導ハイブリッドリポソームの癌治療効果 (化学と生物学の接点がつくるNewバイオテクノロジー) -- (遺伝子発現をあやつる)
- 複合脂質膜の制がんメカニズムと臨床への応用
- 焼酎蒸留粕 (廃液) を利用した新素材転換システムに関する基礎研究 : がん細胞増殖抑制効果
- ハイブリッド型リポソームの種々の腫瘍細胞に対する特異的増殖抑制効果
- 肺癌モデルマウスに対するハイブリッド型リポソームの治療効果
- 制がん性ハイブリッド型リポソームのアポトーシス誘導
- 担癌モデルマウスに対するハイブリッド型リポソームの治療効果
- 牛角利用によるべっ甲代替材料の開発
- 石炭液化油成分の蒸気圧の相関
- アルキルピリジンおよびアルキルピラジンの蒸気圧
- ラセミ体エステルの基質の不斉加水分解反応と制御
- べっ甲成分の基礎分析と端材の有効利用技術
- 人工肝臓開発のための基礎研究--新しいヒト肝幹細胞培養技術と肝機能発現に関する研究
- CLINICAL INVESTIGATION OF THE LIMITING FACTORS OF INFARCT SIZE : Ischemic Heart Disease (II), Coronary Circulation : II : 48 Annual Scientific Meeting, Japanese Circulation Society
- 味噌のがん抑制効果
- 味噌のがん抑制効果
- 1P128 1D1325 Solvent effect on structural stability of human telomere(Nucleic acid:Structure & Property,Oral Presentations,The 48th Annual Meeting of the Biophysical Society of Japan)
- Diastereoselevtive Speficicity for the Hydrolysis of Dipeptide Esters in Aqueous Media
- 脂質系ハイブリッド分子集合体系での人工酵素による立体制御機能
- 人工膜および細胞膜の揺らぎとがん治療 (特集 膜の揺らぎと機能への展開--研究の最前線)
- 1回の速度追跡からその反応の速度式を求めるこころみ
- ジオキサン中p-ニトロソフェノール互変異性混合物のエタノールによる酸触媒エーテル化反応
- 焼酎粕有効成分の美白効果に関する基礎研究
- ミセル系および逆ミセル系におけるエステルの加水分解反応制御
- 水溶液系におけるジペプチドエステル加水分解の立体反応制御
- 種々のミセル系におけるアミノ酸エステルの高選択性不斉加水分解反応
- 2SP5-06 がん細胞膜の揺らぎをターゲットとする制がん効果(2SP5 生体分子の揺らぎをはかる,第47回日本生物物理学会年会)
- 新規ドラッグデリバリ-システムの開発 (特集 新しい研究開発と課題)
- ハイブリッド型リポソームのin Vitroでの抗腫瘍効果
- Isolation and Identification of Sodium 2-Propenyl Thiosulfate from Boiled Garlic (Allium sativum) That Oxidizes Canine Erythrocytes(Organic Chemistry)
- -311-SHORT AND LONG TERM PROGNOSIS IN PATIENTS WITH AMI TREATED WITH CONVENTIONAL AND THROMBOLYTIC THERAPY
- Pathogenesis of Impending Myocardial Infarction and Acute Myocardial Infarction: Clinical and Angiographic Evaluation of Coronary Thrombosis as a Precipitating Factor : SYMPOSIUM ON PATHOGENESIS OF MYOCARDIAL INFARCTION : 49th Annual Scientific Session of
- CORONARY ARTERY LESION AND THE FACTORS CONTRIBUTING TO PRECIPITATION OF ACUTE MYOCARDIAL INFARCTION : Ischemic Heart Disease (III) : FREE COMMUNICATIONS (III) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- PATHOGENESIS AND PROGNOSIS OF IMPENDING MYOCARDIAL INFARCTION : CORONARY ARTERIOGRAPHIC FINDINGS IN UNSTABLE STATE : Ischemic Heart Disease (III) : FREE COMMUNICATIONS (III) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION S
- INTRAVENOUS VS INTRACORONARY UROKINASE THERAPY FOR ACUTE MYOCARDIAL INFARCTION : Ischemic Heart Disease (II) : FREE COMMUNICATIONS (II) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- CLINICAL EVALUATION OF PERCUTANEOUS TRANSLUMINAL RECANALIZATION IN ACUTE MYOCARDIAL INFARCTION : Ischemic Heart Disease (II) : FREE COMMUNICATIONS (II) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- SPECIFIC HYBRID LIPOSOMES COMPOSED OF PHOSPHATIDYLCHOLINE AND POLYOXYETHYLENEALKYL ETHER WITH MARKEDLY ENHANCED INHIBITORY EFFECTS ON THE GROWTH OF TUMOR CELLS IN VITRO
- Nanoparticles of Hybrid Liposomes for the Inhibition of Breast Tumor Growth along with Apoptosis
- Antitumor and Immunostimulatory Effects of Residual Powder from Barley-Shochu Distillation Remnants
- Specific Fixed Aqueous Layer of Three-component Hybrid Liposomes Related to Inhibition of Hepatoma Cells Growth
- Induction of Apoptosis by Hybrid Liposomes for Human Breast Tumor Cells along with Activation of Caspases(Medicinal Chemistry)
- 生命科学をベースとした医療・健康への貢献
- Marked Inhibitory Effects of Extracts from Barley-Koji Miso Encapsulated in Hybrid Liposomes on the Growth of Human Stomach Tumor Cells in Vitro
- Inhibitory Effects of Extracts from Shochu Distillation Remnants on the Growth of Human Stomach Tumor Cells
- Inhibitory Effects of Extracts from Peels of Citrus natsudaidai Encapsulated in Hybrid Liposomes on the Growth of Tumor Cells in Vitro(Medicinal Chemistry)
- Induction and High Density Culture of Human Hepatoblasts from Fetal Hepatocytes with Suppressing Transformation(Molecular and Cell Biology)
- Induction of Apoptosis by Hybrid Liposomes without Antitumor Drugs toward Human Breast Tumor Cells
- Steric-Control for the Enantioselective Hydrolysis of Amino Acid Esters in Hybrid Membrane Systems
- Cyclodextrin-Mediated Deacylation of Amino Acid Esters with Marked Stereoselectivity
- Remarkably Enhanced Inhibitory Effects of Three-Component Hybrid Liposomes Including Sugar Surfactants on the Growth of Lung Carcinoma Cells
- Marked Therapeutic Effect of Dimyristoylphosphatidylcholine Liposomes on Carcinoma Mice Model in Vivo
- Effective Drug Delivery System for Duchenne Muscular Dystrophy Using Hybrid Liposomes Including Gentamicin along with Reduced Toxicity
- Intracellular Responses of Hybrid Liposomes against Leukemia Cells Related to Apoptosis with Antitumor Activity
- Remarkable Salt Effects in the Highly Enhanced Enantioselective Hydrolysis of Amino Acid Esters with the Active Tripeptide in the Vesicular System
- レクチンの認識機能を有するハイブリッド型リポソームの調整
- Therapeutic Effects of Hybrid Liposomes Composed of Phosphatidylcholine and Docosahexaenoic Acid on the Hepatic Metastasis of Colon Carcinoma along with Apoptosis in Vivo
- Specific Interaction between Ca2+ and Anionic Lipids in Cancer Cells along with Apoptosis
- ハイブリッド型人工膜酵素のアミノ酸光学分割機能 (特集 機能性新素材の先端技術)
- Chemotherapy with Hybrid Liposomes for Melanomatosis
- Inhibitory Effects of Hybrid Liposomes Composed of Phosphatidylcholine and Docosahexaenoic Acid on the Growth of Colon Cancer Cells along with Apoptosis and Differentiation
- Clustering of Lipid Rafts in Plasma Membranes by Hybrid Liposomes for Leukemia Cells along with Apoptosis
- Enhancement of drug efflux activity via MDR1 protein by spheroid culture of human hepatic cancer cells(CELL AND TISSUE ENGINEERING)
- イタドリ生理活性物質含有ハイブリッドリポソームのリンパ腫細胞に対する増殖抑制効果
- Therapeutic Effects of Ca2+ on Peritoneal Dissemination of Gastric Carcinoma in Vivo
- REMARKABLE INHIBITORY EFFECTS OF HYBRID LIPOSOMES ON THE GROWTH OF HL-60 CELLS COUPLED TO INDUCTION OF APOPTOSIS
- 人工細胞膜の制がん効果 (化学工学の新潮流)
- 機能性分子集合体を用いたアミノ酸エステル基質の不斉加水分解反応における分子認識効果
- エナンチオマーおよびアステレオマーエステル不斉加水分解の立体制御 : 超分子集合体の新しい展開
- 水溶液系におけるジペプチド基質の高立体選択的加水分解反応制御
- 温州みかん抽出物含有ハイブリッドリポソームの制がん効果に関する研究
- 人工膜および細胞膜の揺らぎとがん治療
- Residual powders from Shochu distillation remnants induce apoptosis in human hepatoma cells via the caspase-independent pathway(MEDICAL BIOTECHNOLOGY)
- 不斉加水分解反応場の熱力学的評価 : ミセルおよび二分子膜系における疎水性相互作用
- Anticancer Effects of Residual Powder from Barley-Shochu Distillation Remnants against the Orthotopic Xenograft Mouse Models of Hepatocellular Carcinoma in Vivo
- Anti-tumor Effects of Cationic Hybrid Liposomes against Colon Carcinoma along with Apoptosis in Vitro
- New Cancer Immunotherapy Using Autologous Lymphocytes Activated with Trastuzumab
- Therapeutic Effects of Autologous Lymphocytes Activated with Trastuzumab for Xenograft Mouse Models of Human Breast Cancer