Anti-tumor Effects of Cationic Hybrid Liposomes against Colon Carcinoma along with Apoptosis in Vitro
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概要
- 論文の詳細を見る
New-type three-component cationic hybrid liposomes (HLs) composed of dimyristoylphosphatidylcholine (DMPC), polyoxyethylene(21)dodecyl ether (C12(EO)21) and O,O′-ditetradecanoyl-N-(α-trimethylammonioacetyl) diethanolamine chloride (2C14ECl) were produced. Cationic HLs were smaller and more stable than pure DMPC liposomes. It is noteworthy that cationic HLs could remarkably inhibit the growth of human colon cancer (HCT116) cells along with apoptosis in vitro for the first time in this study.
- 公益社団法人 日本薬学会の論文
著者
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UEOKA Ryuichi
Division of Applied Chemistry, Graduate School of Kumamoto Institute of Technology
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ICHIHARA Hideaki
Division of Applied Life Science, Graduate School of Engineering, Sojo University
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MATSUMOTO Yoko
Division of Applied Life Science, Graduate School of Engineering, Sojo University
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Hino Motoki
Division of Applied Life Science, Graduate School of Engineering, Sojo University
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