57(P-29) 皮膚炎症に関わる藍の抗菌性物質(ポスター発表の部)

概要

論文の詳細を見る
The yeast Malassezia furfur, present in the normal microflora on human skin, has been known to cause several skin diseases: tinea versicolor, Malassezia folliculitis, seborrheic dermatitis, psoriasis. Recently it has received much attention that M. furfur was reported to be closely related to atopic dermatitis (AD), because it has been observed in patients with head and neck AD and nine allergens have been found from it. On the other hand, in China, Korea and Japan the indigo plant, Polygonum tinctorium, has been used in traditional folk medicine for detoxicatipn, antipyrexia, anti-nociception, anti-inflammation and especially dermatopathy. Interesting in this plant correlated with the effect in dermatopathy, we have searched an antibacterial compound against M. furfur. Finally the high active compound has been isolated and identified as Tryptanthrin.
天然有機化合物討論会の論文
2003-09-01