50 局方モクタール中の抗糸状菌成分

概要

論文の詳細を見る
As one of studies on active principles of tar, antifungal constituents in wood tar (PIX PINI in J.P.VIII.) were examined. Four active principles (2), (3), (4) and (5) were isolated by a suitable combination of column chromatography and two of them, (2) and (3) were designated as Homouchinol and Uchinol, respectively. On the bases of chemical and physico-chemical evidences, uchinol and homouchinol have been determined to have the structure (III) and (IV), respectively. It is some of interest that uchinol belongs to a type of β-diketone is extremely stable under the strongly acidic or basic conditions. To elucidate the stabilities, bond length, bond angle and deviation from the best plane of molecule were examined by X-ray analysis of uchinol, and the reaction of uchinol with diazomethane, amines, carbonyl- and acylating-agents were also investigated.
天然有機化合物討論会の論文
1973-10-01