Intraoperative detection of brain tumors and fluorescent chemonavigation
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概要
- 論文の詳細を見る
Objective : The brain tumors of patients given the compound 5-aminolevulinic acid (5-ALA) were detected by intraoperative fluorescence and surgically removed. Subjects and Methods : Thirty glioma patients were given a single 1 g oral dose of 5-ALA 2 hours before their operations. The target region was exposed to laser light having a peak wavelength of 405 ± 1 nm and an output of 40 mW. Results : Fluorescence was observed in 21 of 30 tumors. No residual tumor remained postoperatively when the red fluorescent region was completely removed. In cases where the tumor could not be completely removed because of the proximity to an eloquent area, the residual tumor was observed postoperatively. Conclusion : The intraoperative fluorescence diagnosis of brain tumors using 5-ALA was very helpful for intraoperative chemonavigation.
- 北里大学の論文
- 2005-09-30
著者
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OKA Hidehiro
Department of Neurosurgery, Kitasato University School of Medicine
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SHIMIZU Satoru
Departments of Neurosurgery Kitasato University School of Medicine
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FUJII Kiyotaka
Departments of Neurosurgery Kitasato University School of Medicine
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TANAKA Satoshi
Department of Physical Science, Osaka Prefecture University
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Tanaka Satoshi
Department Of Nutritional Sciences Faculty Of Nutritional Science Nakamura Gakuen University
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Sato Sumito
Department of Pediatrics, Hirosaki University School of Medicine
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Shimizu Satoru
Department Of Neurosurgery Kitasato University School Of Medicine
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Sato Sumito
Department Of Pediatrics Hirosaki University School Of Medicine
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Fujii Kiyotaka
北里大学 医学部脳神経外科
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Fujii Kiyotaka
Kitasato Univ. School Of Medicine
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Oka Hidehiro
Department Of Laboratory Medicine And Pathology Mayo Clinic
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Sagiuchi Takao
Kitasato Univ. School Of Medicine
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UTSUKI Satoshi
Department of Neurosurgery, Kitasato University School of Medicine
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SUZUKI Sachio
Departments of Neurosurgery
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Utsuki S
Department Of Neurosurgery Kitasato University School Of Medicine
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Utsuki Satoshi
Department Of Neurosurgery Kitasato University School Of Medicine
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Fujii Kiyotaka
Department Of Brain Sugery School Of Medicine Kitasato University
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Suzuki Sachio
Department Of Neurosurgery Kitasato University School Of Medicine
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Oka Hidehiro
Department Of Neurosurgery School Of Medicine Kitasato University
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Shimizu Satoru
Department Of Neurosurgery Yokohama Stroke And Brain Center
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Tanaka Satoshi
Department Of Anesthesia Nagano Municipal Hospital
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Shimizu Satoru
Department Of Hygiene And Public Health I Tokyo Women's Medical University
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Shimizu Satoru
Kitasato Univ. School Of Medicine Kanagawa Jpn
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Tanaka Satoshi
Department Of Neurosurgery The Kitasato Institute Medical Center Hospital
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Tanaka Satoshi
Department Of Agricultural Chemistry Faculty Of Agriculture Tottori University
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Shimizu Satoru
Department Of Biotechnology Faculty Of Engineering Kyoto Sangyo University
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Sato Sumito
Department of Neurosurgery, Yokohama Stroke and Brain Center
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