Constituent Properties of Licorices Derived from Glycyrrhiza uralensis, G. glabra, or G. inflata Identified by Genetic Information(Pharmacognosy)

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概要

• 論文の詳細を見る

• Constituent properties of licorices derived from Glycyrrhiza uralensis, G. glabra, and G. inflata are revealed by comparing 117 of licorice identified using four genetic markers; internal tracscribed spacer (ITS) on nuclear ribosomal DNA, rbcL gene, matK gene, and trnH-trnKl intergenic region on chloroplast DNA. Regarding six main constituents of licorice; glycyrrhizin, liquiritin, liquiritin apioside, isoliquiritin, isoliquiritin apioside, and liquiritigenin, the constituent property of G. glabra resembles to that of G. inflata. On the other hand, the constituent property of G. uralensis is not similar to that of G. glabra or G. inflata and is characterized by a wide content variation of the six constituents compared to those of G. glabra and/or G. inflata. The mean contents of liquiritin, isoliquiritin, or liquilitigenin in G. uralensis are significantly higher than those of G. glabra or G. inflata. Therefore, the licorice species should be selected depending on these constituent properties for the traditional Chinese medicines or the Japanese Kampo medicines. Additionally, glycycoumarin, glabridin, and licochalcone A were reconfirmed as the species-specific typical constituents of G. uralensis, G. glabra, and 6". inflata respectively. Therefore, it is resulted that the determination of the three species-specific constituents may be useful for the species identification of licorice. However, since 6% of licorice examined and hybrids were exceptions to the rule, their genetic information is necessary for the accurate species identification of licorice.

• 公益社団法人日本薬学会の論文
• 2007-07-01

著者

• Kondo Kenji

  Botanical Raw Materials Research Dept. Tsumura & Co.

• Morota Takashi

  Botanical Raw Materials Research Department Tsumura & Co.

• Morota Takashi

  Botanical Raw Materials Research Dept. Tsumura & Co.

• SHOYAMA Yukihiro

  Graduate School of Pharmaceutical Sciences, Kyushu University

• SHIBA Mao

  Botanical Raw Materials Research Department, Tsumura & Co.

• NAKAMURA Rie

  Botanical Raw Materials Research Dept., Tsumura & Co.

• Nakamura Rie

  Botanical Raw Materials Research Dept. Tsumura & Co.

• Morota Takashi

  Pharmacognosy And Medicinal Resources Research Department Central Research Laboratories Tsumura &

• Shoyama Yukihiro

  Graduate School Of Pharmaceutical Sciences Kyushu University

• Shiba Mao

  Botanical Raw Materials Research Dept. Tsumura & Co.

• Kondo Kenji

  Pharmacognosy Department Tsumura & Co.

• Morota Takashi

  Botanical Raw Materials Research Department Botanical Raw Materials Division Tsumura & Co.

• Nakamura Rie

  Botanical Raw Materials Division Tsumura & Co.

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