Cranial Bone Regeneration by Controlled Release of Platelet Growth Factors from Biodegradable Hydrogel(International Symposium of Maxillofacial and Oral Regenerative Biology in Okayama 2005)

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概要

• 論文の詳細を見る

• Recently, platelet-rich plasma (PRP) has been clinically employed to promote bone repairing. However, little has been investigated on the materials combination of PRP to enhance the biological function of growth factors present in platelets. In this study, feasibility of gelatin hydrogels in the controlled release of platelet growth factors and the consequent enhancement of PRP-induced bone regeneration were evaluated by a cranial bone defect model of rabbits. In conclusion, the gelatin hydrogel achieved the controlled release of bioactive platelet growth factors to significantly promote bone regeneration, in marked contrast to PRP alone.

• 硬組織再生生物学会の論文

著者

• tabata yasuhiko

  Department of Biomaterials, Institute for Frontier Medical Science, Kyoto university

• Morita Shosuke

  First Department of Oral and Maxillofacial Surgery, Osaka Dental University

• Morita Shosuke

  First Department Of Oral And Maxillofacial Surgery Osaka Dental University

• Hokugo Akishige

  Department Of Biomaterials Field Of Tissue Engineering Institute For Frontier Medical Sciences Kyoto

• Tabata Yasuhiko

  Department Of Biomaterials Field Of Tissue Engineering Institute For Frontier Medical Sciences Kyoto

• Sawada Yasunori

  First Department of Oral and Maxillofacial Surgery, Osaka Dental University

• Mushimoto Kozo

  First Department of Oral and Maxillofacial Surgery, Osaka Dental University

• Mushimoto Kozo

  First Department Of Oral And Maxillofacial Surgery Osaka Dental University

• Tabata Yasuhiko

  Department Of Biomaterials Field Of Tissue Engineering Institute For Frontier Medical Sciences Kyoto

• Sawada Yasunori

  First Department Of Oral And Maxillofacial Surgery Osaka Dental University

• Hokugo Akishige

  Department Of Biomaterials Field Of Tissue Engineering Institute For Frontier Medical Sciences Kyoto

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