Enzyme Immunoassay による Carbamazepine ならびに Ethosuximide の血中濃度測定 : Gas-Liquid Chromatography による測定値との比較

概要

論文の詳細を見る
Recently a simple and rapid enzyme-multiplied immunoassay technique (EMIT) became available for the determination of antiepileptic drugs. Plasma specimens from patients on carbamazepine (CBZ) or ethosuximide (ESM) therapy were determined in each of drugs by EMIT and published gas-liquid chromatographic procedure (GLC). Both procedures were done with commercially available materials and equipments. Results by the two procedures agreed well, which suggests that the two methods could be used interchangeably. For each of the 30 specimens studied for CBZ and ESM, the correlation coefficient was 0.981 and 0.995, respectively.
北里大学の論文
1978-04-30