Molecular Properties of Cholera Enteroxin
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概要
- 論文の詳細を見る
The molecular properties of Vibrio cholerae enterotoxin obtained from two different insitutions were studied. The preparations, which were purified by different methods, showed the same physicochemical properties. Ultracentrifugal analysis showed that the toxin had a molecular weight of 79,000, a sedimentation coefficient of 5.25 S and a diffusion coefficient of 6.02 D. When the toxin was subjected to polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate, the A subunit with an apparent molecular weight of 31,000-32,000 was observed. Based of these findings and the molecuar weight of the B subunit of 11,604 which was calculated from its primary structure, it is proposed that holotoxin is composed of one A subunit and four B subunits.
- 東海大学の論文
著者
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SASAKI Shogo
Department of Microbiology, School of Medicine, Tokai University
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Ozawa Atsushi
Department Of Cardiology St. Marianna University Yokohama City Seibu Hospital
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Ozawa Atsushi
Department Of Microbiology School Of Medicine Tokai University
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Sasaki Shogo
Department Of Infectious Disease Tokai University School Of Medicine Isehara
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OKAJIMA Yoshiaki
Division of Clinical Microbiology, School of Medicine, Tokai University
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SHIMAMURA Tadakatsu
Division of Clinical Microbiology, School of Medicine, Tokai University
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Okajima Yoshiaki
Division Of Clinical Microbiology School Of Medicine Tokai University
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Ozawa Atsushi
Department Of Bacteriology 2nd National Tokyo Hospital
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OZAWA Atsushi
Department of Microbiology, School of Medicine, Tokai University
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SASAKI SHOGO
Department of Bacteriology, School of Medicine, Keio University
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