尿および血漿アミノ酸両値の比較的研究 : (第1編)両値間パターンの加令的変化

概要

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The amino acid excretion in a 24-hour urine-sample was quantitated in 15 neonates, 22 infants, and 20 preschool or school children, after previous calibration of plasma amino acids. The excretion of many of 17 amino acids increased with the age, although the degree for the individuals were very different. The significant age-dependent increase from neonatal period till school age was noticed in histidine, threonine (threonine+glutamine+asparagine), and tyrosine; the significant increasing from infancy till childhood in lysine, glycine, methionine, leucine, and phenylalanine; the slight degree increase with aging in arginine, aspartic acid, serine, glutamic acid, alanine, cystine, valine, and isoleucine, while the decrease in proline. Furthermore, the combination of urinary and plasma amino acid values were illustrated in figures in 40 various disease infants and children without renal dysfunction, additionally in a child with renal hyperaminoaciduria. The notable change in the pattern of both value combination was shown in lysine, glycine, tyrosine, threonine (threonine+glutamine+asparagine), alanine, and histidine; the slight notice in serine, glutamic acid, cystine, and proline; no change in arginine, aspartic acid, methionine, valine, leucine, isoleucine, and phenylalanine.
北里大学の論文
1977-04-30