Cylic Guanidines. VIII. Synthesis of Imidazo-1,3- and -2,4-benzodiazepine Derivatives as Blood Platelet Aggregation Inhibitors
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概要
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The imidazo [2,1-b] [1,3]- and -[2,4] benzodiazepin-2-one derivatives (4) and (13), and imidazo [1,2-α] [1,3] benzodiazepin-2-one derivative (9), of a potent blood platelet aggregation inhibitor, the imidazo [2,1-b] quinazolin-2-one derivative (14), were synthesized as ring expansion analogs. Compound 9 showed potent activity but 4 and 13 showed poor activity and no activity, respectively.
- 公益社団法人日本薬学会の論文
- 1980-04-25
著者
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渡辺 好文
Daiichi Pharmaceutical Co. Ltd. Research Institute
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石川 文義
Research Institute, Daiichi Seiyaku Co., Ltd.
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渡辺 好文
Research Institute, Daiichi Seiyaku Co., Ltd.
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石川 文義
Research Institute Daiichi Seiyaku Co. Ltd.
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