Cyclic Guanidines. IX. Synthesis of 2-Amino-3,4-dihydroquinazolines as Blood Platelet Aggregation Inhibitors
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概要
- 論文の詳細を見る
A series of aryl-or aralky-substituted 2-amino-3,4-dihydroquinazolines and related compounds were synthesized. The compounds were evaluated for inhibitory activity towards collagen-and ADP-induced aggregation of rat blood platelet in vitro and ex vivo. A group of 3-benzyl-substituted derivatives had potent activity. The structure-activity relationships are discussed.
- 公益社団法人日本薬学会の論文
- 1980-05-25
著者
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渡辺 好文
Daiichi Pharmaceutical Co. Ltd. Research Institute
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渡辺 好文
Research Institute, Daiichi Seiyaku Co., Ltd.
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石川 文美
Research Institute, Daiichi Seiyaku Co., Ltd.
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三枝 順二
Research Institute, Daiichi Seiyaku Co., Ltd.
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石川 文美
Research Institute Daiichi Seiyaku Co. Ltd.
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三枝 順二
Research Institute Daiichi Seiyaku Co. Ltd.
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