Mechanism of Color Reaction of Aromatic Secondary and Tertiary Amines with Quinonedichlorodiimide
スポンサーリンク
概要
- 論文の詳細を見る
Quinonedichlorodiimide (I) reacts with aromatic secondary and tertiary amines to yield green colored compounds. The chemical structure of these colored compounds is investigated from the spectral data (infrared, ultraviolet, nuclear magnetic resonance, mass) and the chemical reactions. The color of the reaction product of I and N-ethyl-m-toluidine (II) or N, N-diethyl-m-toluidine (III) is changed mutually between green and violet by oxidation and reduction. These results and the spectral data suggest that these reactions are electrophilic displacement reactions in the ortho or para position of the alkylamino group and I reacts with II or III at the rate of 1 : 2.
- 1979-03-25
著者
-
宇野 豊三
Faculty of Pharmaceutical Sciences, Kyoto University
-
山本 正康
Chemical Laboratory College Of General Education Nagoya City University
-
宇野 豊三
Faculty Of Pharmaceutical Sciences Kyoto University
関連論文
- On the Retention Index
- Absorption Kinetics of Carbenicillin Phenyl Sodium and Carbenicillin Indanyl Sodium in Man
- New Method for the Evaluation of in Vitro Dissolution Time and Disintegration Time
- High Performance Liquid Chromatographic Determination and Pharmacokinetic Investigation of Amino-penicillins and Their Metabolites in Man
- Isolation and Structural Investigation of the Fluorescent Degradation Products of Ampicillin
- Comparative Pharmacokinetics of Metabolism and Urinary Excretion of Isoxazolylpenicillins in Man
- Pharmacokinetic Studies of the Urinary Excretion of Clavulanic Acid in Man
- High Performance Liquid Chromatographic Analysis and Pharmacokinetic Investigation of Oxacillin and Its Metabolites in Man
- Evaluation of Effect of Food Ingestion on Bioavailability of Cephalexin by Moment Analysis
- Reaction Products of Sulbactam with Pyrazole, 1,2,4-Triazole and Imidazole : High-Performance Liquid Chromatographic Behavior and Structural Investigation
- Degradation Kinetics of Sodium Sulbactam in Aqueous Solutions
- Alkaline Degradation of Sulbactam
- Fast Atom Bombardment Mass Spectrometry of Isoxazolylpenicillins and Their Metabolites in Man
- Degradation of Clavulanic Acid in Aqueous Alkaline Solution : Isolation and Structural Investigation of Degradation Products
- Structure Confirmation of Active Metabolite of Dicloxacillin in Man by Nuclear Magnetic Resonance Spectroscopy
- Sulbactam : Alkaline Degradation and Determination by High-Performance Liquid Chromatography
- Determination of Rate Constants for Formation and Decomposition of Color Products in the Fujiwara Reaction Using Benzotrichloride
- Alkaline Degradation of Clavulanic Acid and High Performance Liquid Chromatographic Determination by Post-Column Alkaline Degradation
- Isolation and Structural Investigation of the Chromophore in the Fujiwara Reaction as Applied to Chloramphenicol
- DEGRADATION OF CLAVULANIC ACID IN AQUEOUS ALKALINE SOLUTION
- The Fujiwara Reaction : Isolation and Structural Investigation of the Reaction Product from Chloroform
- Stability of Clavulanic Acid in Aqueous Solutions
- Studies on Imidazole Derivatives as Chelating Agents. III. Syntheses of Schiff Bases and 4 (5)-Aminomethyl Derivatives and Their Reactions with Metal Ions.
- Studies on Imidazole Derivatives as Chelating Agents. II. Spectrophotometric and Potentiometric Investigations of Acid-base Equilibria of Azoimidazoles
- Studies on Imidazole Derivatives as Chelating Agents. I. Syntheses of Azoimidazoles and Their Reactions with Metal Ions
- Studies on the Metabolism of Sulfadiazine. I. On the Separation and Identification of Excrements in Human Urine after its Oral Administration.
- Infrared Spectra of Sulfonamide Derivatives. I. Pyridine, Thiazole, and Pyrimidine Derivatives.
- Studies on Benzothiazole Derivatives as Chelating Agents. V. Fluorescence of Benzothiazole Derivatives and Their Zinc Chelates
- Studies on Benzothiazole Derivatives as Chelating Agents. IV. Coordination to Divalent Metal Ions
- Studies on Benzothiazole Derivatives as Chelating Agents. III. Acid-base Equilibria and Chelate Formation with Metal Ions
- Studies on Benzothiazole Derivatives as Chelating Agents. II. The Fluorometric Determination of Zinc with N-Salicylidene-4-aminobenzothiazole
- Studies on Benzothiazole Derivatives as Chelating Agents. I. Syntheses of Benzothiazole Derivatives and Their Reactions with Metal Ions
- Infrared Spectra of Sulfonamide Derivatives. II. Thiophene, Thiadiazole, and Isoxazole Derivatives
- Determination of Surface-active Agents. VIII. Infrared Determination of the Proportion of Ethylene Oxide and Propylene Oxide in Pluronic
- Structural Investigation of New Metabolites of Aminopenicillins excreted in Human Urine
- Studies on the Metabolism of Sulfadimethoxine. II. Determinations of Metabolites in Human and Rabbit Urine after Oral Administration of Sulfadimethoxine.
- GC-MS Identification of Active Metabolite of Oxacillin in Man
- Mechanism of Color Reaction of Aromatic Secondary and Tertiary Amines with Quinonedichlorodiimide
- キノンジクロルジイミドによるキノホルムの定量法
- Studies on the Metabolism of Sulfadiazine. II. Quantitative Separation of Excrements in the Human Urine after Administration of Sulfadiazine
- Studies on the Metabolism of Sulfathiazole. IV. A New Sulfathiazole-glucuronic Acid Conjugate in the Human Urine.
- Infrared Spectra of α-Bromoacylureas and Their N, N'-Deuterated Compounds
- Studies on the Metabolism of Sulfadimethoxine. I. On the Excreted substance in the Human Urine after Oral Administration of Sulfadimethoxine
- Determination of Surfaceactive Agents. VII. Differential Determination of Cationics and Nonionics in Mixture.
- Color Reaction Mechanism of Chinoform by Quinonedichlorodiimide
- Colorimetric Determination and Detection of Tertiary Amines with cis-Aconitic Anhydride
- キノンジクロルジイミドによるスルピリンのけい光定量法
- キノンジクロルジイミドによるアミン類の呈色反応および定量法
- 二級アミンの比色定量法
- Determination of Surface-active Agents. VI. On the Composition of Nonionics-Barium-Tetraphenylborate Complex.
- Determination of Surfaceactive Agents. V. Volumetric Determination of Ethylene Oxide Content in Nonionic Surface-active Agent.
- Determination of Surface-active Agent. III. Volumetric Determination of Anionic Surface-active Agent using Neutral Red as an Indicator.
- Volumetric Determination of Surfaceactive Quaternary Ammonium Salts using Marme's Reagent.