Studies on the Metabolism of Sulfadimethoxine. II. Determinations of Metabolites in Human and Rabbit Urine after Oral Administration of Sulfadimethoxine.
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概要
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The concentration and the amounts of sulfadimethoxine metabolites in both human and rabbit urine were determined separately using paper chromatography for 168 hours after administration. In human urine the main metabolite was sulfadimethoxine-N^1-glucuronide, and more than 70% of the whole metabolites was excreted in this form. In the case of rabbit, the main metabolite was N^4-acetyl sulfadimethoxine.
- 公益社団法人日本薬学会の論文
- 1967-09-25
著者
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宇野 豊三
Faculty Of Pharmaceutical Sciences Mukogawa Women's University
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平岡 孝
Products Development Laboratories Sankyo Co. Ltd.
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宇野 豊三
Faculty Of Pharmaceutical Sciences Kyoto University
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