Studies on Nucleosides and Nucleotides. VIII. Nucleophilic Substitution of Secondary Sulfonyloxy Groups of Pyrimidine Nucleosides. (1)
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概要
- 論文の詳細を見る
Treatment of 2'-O-tosyl-5'-O-trityluridine (I), 2'-O-tosyluridine (II), or 2', 3'-di-O-tosyluridine (XI) with various alkali chlorides or bromides afforded only 2'-halogenonucleosides, whereas in the reaction of alkali iodides with I or II were isolated 2,2'-anhydronucleosides accompanied with 2'-deoxy-2'-iodouridine derivatives. And in the reaction of XI with sodium iodide in DMF only 2,2'-anhydro-1-(3'-O-tosyl-β-D-arabinofuranosyl)-uracil (XIII) was obtained.
- 社団法人日本薬学会の論文
- 1968-02-25
著者
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小林 利彦
Central Research Laboratory Daiichi Seiyaku Co. Ltd.
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中井 義昭
Central Research Laboratory Daiichi Seiyaku Co. Ltd.
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内藤 武男
Central Research Laboratory, Daiichi Seiyaku Co., Ltd.
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平田 三四司
Central Research Laboratory, Daiichi Seiyaku Co., Ltd.
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金尾 宗史
Central Research Laboratory, Daiichi Seiyaku Co., Ltd.
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金尾 宗史
Daiichi Pharmaceutical Co., Ltd.,
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内藤 武男
Research Laboratories, Daiichi Seiyaku Co., Ltd.
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内藤 武男
Research Laboratories Daiichi Seiyaku Co. Ltd.
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平田 三四司
Research Institute, Daiichi Seiyaku Co., Ltd.
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平田 三四司
Research Institute Daiichi Seiyaku Co. Ltd.
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金尾 宗史
Daiichi Pharmaceutical Co. Ltd.
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平田 三四司
Central Research Laboratory Daiichi Seiyaku Co. Ltd.
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