Cohesion of Particulate Solids. VIII. Influence of Particle Shape on Compression by Tapping

概要

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The influence of particle shape of granules or powder on tapping compaction behavior has been studied. Several kinds of samples, glass beads and glass powder, intact lactose granules and spherical lactose granules etc., where the same material was made into different shapes, were used.The diameter of the particles and the shape factor were measured. Most of the samples showed three compaction lines (lines 1-3), irrespective of the shape of the granules.The segments of the three compaction lines (k_1,k_2 and k_3) of glass powder were significantly larger than those of glass beads. The segments of line 3,(k_3), of the rounded granules were smaller than those of intact granules.Dependency on the shape of the particles was noted in the three tapping compaction lines.A case in which tapping compaction behavior could not be adapted to a straight line was reported. In this case, special particles were considered.
公益社団法人日本薬学会の論文
1992-10-25