粉粒体の凝集性(第1報) : 凝集力の測定方法(薬剤学)

概要

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A quantitative method was devised for measuring the interparticle cohesive force in a loosely packed powder bed. A particulate solid was packed in a vessel without applying an external compressive force. A small disk with thin layer of an adhesive agent on its lower surface was placed on the surface of the packed bed applying a slight pressure so that the surface particles of the bed would stick to the disk. The disk was then pulled out and the minimal force, F_t, required to remove the particles sticking to the disk from the surrounding particles was measured by a torsion balance. The apparent cohesiveness, α_c, is defined by the equation α_c=F/W, where F is (F_t-W) and W is the weight of the particles sticking to the disk. The effect of disk area, load, and nature of adhesive agent on the values of F were measured and the optimal conditions were determined as 0.24 cm^2 of disk area, 400 mg/cm^2 of load, and the petrolatum as the adhesive agent. It is suggested that the force, F, obtained by this method is the total value of four type forces, that is, adhesive force, f^A, leaning force, f^L, entanglemental force, f^E, and defacing force, f^D.
公益社団法人日本薬学会の論文
1972-01-25