非水溶液における呈色反応(第3報) : スルホンフタレイン系色素と第三級アミン類との呈色反応および溶媒効果

概要

論文の詳細を見る
Color reaction of bromophenol blue (H_2A) with tertiary amines (B) in non-aqueous solvents was examined and this reaction was compared with that in ethyl acetate. This reaction in benzene, dioxan, and tetrahydrofuran is similar to that in ethyl acetate, but the reaction in methanol, ethanol, and acetone is different. Molecular coefficients and equilibrium constants in the former solvents were determined from equations (1) and (2), and the solvent effect on this reaction was examined. H_2A+B⇌BH^+・HA^- K_1=[BH^+・HA^-]/[H_2A]・[B] BH^+・HA^-+B⇌BH^+(BH^+・A^<2->) K_2=[BH^+(BH^+・A^<2->)]/[BH^+・HA]・[B] In this case seven kinds of amines including trimethylamine, triethylamine, and dimethylcyclohexylamine, were used. Examination of the color reaction of sulfonephthalein dyes other than bromophenol blue with tertiary amines in benzene and methanol showed that bromophenol blue, in which the acidity of phenolic hydroxyl was greatly strengthened by bromine in the ortho-position, indicated a high reactivity and was the best dye for reaction with amines.
公益社団法人日本薬学会の論文
1971-12-25