液・固クロマトグラフィーにおけるアミノ-およびシアノ-アルキル結合シリカの特性化(第2報)ステロイドを溶質とする強成分溶媒の相対強度

概要

論文の詳細を見る
As a continuation of our work on the characterization of chemically bonded phases by using ethyl acetate as a stronger solvent in an n-hexane-binary system, the retention behaviors of fifteen steroid hormones were systematically examined in an ethanolcontaining binary eluent. On the basis of a linear relationship between the logarithm of the capacity ratio and that of the solvent composition, the retentivities of amino, cyano and bare silica columns were determined. These columns all showed similar affinity, and stronger adsorption was observed for phenolic solutes while weaker adsorption was shown for acyl derivatives in the case of amino-type columns than that for other columns. The relative solvent strength of ethanol to ethyl acetate in n-hexanebinary solvents was confirmed by use of these three columns. The relative strength of ethanol to ethyl acetate increased especially in amino-type and bare silica columns.
公益社団法人日本薬学会の論文
1983-07-25