NOVEL DETECTION METHOD OF NITRIC OXIDE USING HORSERADISH PEROXIDASE

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概要

• 論文の詳細を見る

• Nitric oxide (NO) readily makes corresponding complexes not only with ferrous iron but also with ferric iron. However, NO-ferric complexes of many heme proteins were unstable, while horseradish peroxidase formed the very stable NO-ferric porphyrin complex with a shift of the Soret band of the absorption wavelength from 396.5 nm to 420.0 nm. The concentration of NO in aqueous media could be monitored by measuring the absorption changes, and the detection limit was 10 nM. The simple procedure is convenient for concentration determination of NO solution.

• 公益社団法人日本薬学会の論文
• 1996-04-15

著者

• NAGANO Tetsuo

  Faculty of Pharmaceutical Science, University of Tokyo

• HIROBE Masaaki

  Graduate School of Pharmaceutical Sciences, The University of Tokyo

• HIROBE Masaaki

  Faculty of Pharmacuetical Sciences, University of Tokyo

• Hirobe M

  Graduate School Of Pharmaceutical Sciences The University Of Tokyo

• Hirobe Masaaki

  Faculty Of Pharmaceutical Science University Of Tokyo

• Kikuchi K

  Graduate School Of Pharmaceutical Sciences The University Of Tokyo:presto Jst Corporation

• Kikuchi Kazuya

  Faculty Of Pharmaceutical Sciences University Of Tokyo

• Nagano Tetsuo

  Faculty Of Pharmaceutical Science University Of Tokyo

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