Hydroxylation of Nitrated Naphthalenes with KO_2/Crown Ether

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概要

• 論文の詳細を見る

• Superoxide radical anion (O^<・->_2), generated by KO_2/crown ether, is effective for hydroxylation of nitronaphthalenes. When mono- and di-nitronaphthalenes are treated with KO_2/crown ehter, hydroxylation results at the electron-deficient site caused by the electron withdrawing effect of the substituted nitro group. Kinetic experiments suggest that the hydroxylation proceeds by two different mechanisms dependent on the first one-electron reduction potential of nitronaphthalenes.

• 公益社団法人日本薬学会の論文
• 2000-10-01

著者

• 宮田 直樹

  名古屋市立大学

• MIYATA Naoki

  Division of Organic Chemistry, National Institute of Health Sciences

• FUKUHARA Kiyoshi

  Division of Organic Chemistry, National Institute of Health Sciences (NIHS)

• Miyata Naoki

  Division Of Organic Chemistry National Institute Of Health Sciences

• Ikuo Nakanishi

  Radiation Modifier Research Team Heavy-ion Radiobiology Research Group Research Center For Charged P

• Fukuhara Kiyoshi

  Division Of Organic Chemistry National Institute Of Health Sciences (nihs)

• Fukuhara Kiyoshi

  Division Of Organic Chemistry

• Fukuhara Kiyoshi

  Div. Of Organic Chem. Natl. Inst. Health Sci.

• HARA Yukie

  Division of Organic Chemistry, National Institute of Health Sciences

• NAKANISHI Ikuo

  Division of Organic Chemistry, National Institute of Health Sciences

• Miyata Naoki

  Division Of Organic Chemistry

• Hara Yukie

  Division Of Organic Chemistry National Institute Of Health Sciences

• Fukuhara Kiyoshi

  Div. Of Organic Chemistry National Inst. Of Health Sciences

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