Thermal Addition Reaction of Aroylketene with 1-Aryl-1-trimethylsilyloxyethylenes : Aromatic Substituent Effects of Aroylketene and Aryltrimethylsilyloxyethylene on Their Reactivity

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概要

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• The thermal addition reaction of various aroylketenes (C) generated by the thermolysis of 5-aryldioxofurans (A) to 1-aryl-1-trimethylsilyloxyethylenes gave 1,5-diarylpentane-1,3,5-triones (D) and 2,6-diaryl-4H-pyran-4-ones (E). The introduction of electron withdrawing substituents in the aroylketene and of electron donating substituents facilitated the addition reaction. The observed substituent effects and the reaction mechanism are interpreted in terms of molecular orbital analyses.

• 公益社団法人日本薬学会の論文
• 1996-05-15

著者

• 尾山 力

  Tsumura Central Research Laboratories Tsumura & Co.

• 佐野 武弘

  昭和薬科大学

• 佐野 武弘

  Showa Pharmaceutical Univ. Tokyo Jpn

• SANO Takehiro

  Showa College of Pharmaceutical Sciences

• SAITOH Toshiaki

  Showa College of Pharmaceutical Sciences

• HORIGUCHI Yoshie

  Showa College of Pharmaceutical Sciences

• TODA Jun

  Showa College of Pharmaceutical Sciences

• Toda J

  Showa Coll. Pharmaceutical Sci. Tokyo Jpn

• OYAMA Taichi

  Showa College of Pharmaceutical Sciences

• SAKURAI Kiyomi

  Showa College of Pharmaceutical Sciences, Higashi-tamagawagakuen

• NIIMURA Yosihiro

  Showa College of Pharmaceutical Sciences, Higashi-tamagawagakuen

• HINATA Mitsuru

  Showa College of Pharmaceutical Sciences, Higashi-tamagawagakuen

• Horiguchi Y

  Showa Pharmaceutical University

• Oyama T

  Showa College Of Pharmaceutical Sciences Higashi-tamagawagakuen

• Hinata Mitsuru

  Showa College Of Pharmaceutical Sciences Higashi-tamagawagakuen

• Niimura Yosihiro

  Showa College Of Pharmaceutical Sciences Higashi-tamagawagakuen

• Sakurai Kiyomi

  Showa College Of Pharmaceutical Sciences Higashi-tamagawagakuen

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