Alkaloidal Constituents of the Leaves of Stephania cepharantha Cultivated in Japan : Structure of Cephasugine, a New Morphinane Alkaloid
スポンサーリンク
概要
- 論文の詳細を見る
From the leaves of Stephania cepharantha HAYATA (Menispermaceae) cultivated in Japan, a new morphinane alkaloid, cephasugine (1), was isolated together with 14 known alkaloids. The structure of 1 was elucidated as the N-methyl derivative of sinococuline (17) by comparison of spectroscopic data with those of cephakicine (16). This is the first report of the alkaloidal constituents of the leaves of S. cepharantha.
- 公益社団法人日本薬学会の論文
- 1997-03-15
著者
-
鈴木 秀行
原町赤十字病院 内科
-
Ono Mayumi
Department Of Pharmaceutical Oncology Graduate School Of Pharmaceutical Sciences Kyushu University
-
Ono M
Departments Of Biochemistry Kyushu University School Of Medicine
-
Suzuki Hideshi
Pharmaceutical Research Laboratories Kyowa Hakko Kogyo Co. Ltd.
-
Ono M
Kyushu Tokai Univ. Kumamoto Jpn
-
Ono M
Analytical Laboratory Self-medication Laboratories Taisho Pharmaceutical Co. Ltd.
-
Ono Minoru
Research Laboratories Kaken Shoyaku Co. Ltd.
-
佐野 武弘
昭和薬科大学
-
Suzuki H
Showa College Of Pharmaceutical Sciences
-
佐野 武弘
Showa Pharmaceutical Univ. Tokyo Jpn
-
SANO Takehiro
Showa College of Pharmaceutical Sciences
-
TODA Jun
Showa College of Pharmaceutical Sciences
-
KASHIWABA Noriaki
Research Laboratories, Kaken Shoyaku Co., Ltd.,
-
MOROOKA Shigeo
Research Laboratories, Kaken Shoyaku Co., Ltd.,
-
SUZUKI Hideki
Showa College of Pharmaceutical Sciences
-
Ono Masaki
Analytical Laboratory Self-medication Laboratories Taisho Pharmaceutical Co. Ltd.
-
Suzuki H
Janssen Pharmaceutical K.k. Shizuoka Jpn
-
Toda J
Showa Coll. Pharmaceutical Sci. Tokyo Jpn
-
Ono M
Faculty Of Pharmaceutical Sciences Tokushima Bunri University
-
Morooka S
Research Laboratories Kaken Shoyaku Co. Ltd.
-
Kashiwaba N
Kaken Shoyaku Co. Ltd. Tokyo Jpn
-
Kashiwaba Noriaki
Research Laboratories Kaken Shoyaku Co. Ltd.
関連論文
- プレドニゾロンのジェネリック医薬品への変更により増悪した自己免疫性肝炎の1例
- 最近5年間の劇症肝炎例での肝移植適応例に関する検討
- Ets regulates peroxiredoxin1 and 5 expressions through their interaction with the high-mobility group protein B1
- Inhibition of bone and muscle metastases of lung cancer cells by a decrease in the number of monocytes/macrophages
- Inflammatory stimuli from macrophages and cancer cells synergistically promote tumor growth and angiogenesis
- Direct inhibition of EGF receptor activation in vascular endothelial cells by gefitinib ('Iressa', ZD1839)
- THE BASIC AND CLINICAL IMPLICATIONS OF ABC TRANSPORTERS, Y-BOX-BINDING PROTEIN-1 (YB-1) AND ANGIOGENESIS-RELATED FACTORS IN HUMAN MALIGNANCIES
- All-trans-retinoic Acid-dependent Inhibition of E-Cadherin-based Cell Adhesion with Concomitant Dephosphorylation of β-Catenin in Metastatic Human Renal Carcinoma Cells
- Microtubule Reorganization and Lysosome Redistribution by a Viral v-src Oncogene, in Mouse Balb/3T3 Cells Expressing Human EGF Receptor
- Direct inhibition of EGF receptor activation in vascular endothelial cells by gefitinib ('Iressa', ZD1839)
- Direct inhibition of EGF receptor activation in vascular endothelial cells by gefitinib ('Iressa', ZD1839)
- 4. 生体肝移植を施行したHBc抗体陽性肝内結石合併肝硬変症の1例
- Direct inhibition of EGF receptor activation in vascular endothelial cells by gefitinib ('Iressa', ZD1839)
- Direct inhibition of EGF receptor activation in vascular endothelial cells by gefitinib ('Iressa', ZD1839)
- Molecular links between tumor angiogenesis and inflammation : inflammatory stimuli of macrophages and cancer cells as targets for therapeutic strategy
- -0759- SHORT-TERM TICLOPIDINE WITHOUT WARFARIN AFTER PALMAZ-SHATZ CORONARY STENTING(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)
- 10. 十二指腸水平脚の憩室出血を内視鏡的に止血し得た一例(第19回群馬消化器内視鏡医の集い)
- NOVEL BIOTRANSFORMATION OF A 2-PYRONE TO A SUBSTITUTED BENZOIC ACID
- High expression of insulin-like growth factor binding protein-3 is correlated with lower portal invasion and better prognosis in human hepatocellular carcinoma
- Direct inhibition of EGF receptor activation in vascular endothelial cells by gefitinib ('Iressa', ZD1839)
- 某製造工場における腰痛と作業姿勢及び生活習慣との関係
- Work Ability Indexと認知機能検査の比較検討
- Work Ability Indexと職種との関連性について
- The relationship between WAI and cognitive functions in a manufactory (産業保健人間工学会第8回大会特集) -- (Session 4 IEA session No. S017: Ergonomics Actions in Occupational Health)
- WAIを用いた労働能力評価と暦年齢の比較研究 (産業保健人間工学会第7回大会特集)
- Composite Constituents : Three New Triterpene Triols Isolated from Fresh Roots of Picris hieracioides subsp. japonica
- Composite Constituents : Forty-Two Triterpenoids Including Eight Novel Compounds Isolated from Picris hieracioides subsp. japonica
- COMPOSITE CONSTITUENT : NOVEL TRITERPENOID, IXERENOL, FROM AERIAL PARTS OF IXERIS CHINENSIS
- COMPOSITE CONSTITUENT : NOVEL TRITERPENOID, 17-EPI-LUPENYL ACETATE, FROM AERIAL PARTS OF IXERIS CHINENSIS
- NMR Spectra of Triterpenoids. II. Hopenes and Migrated Hopenes
- NMR Spectra of Triterpenoids. I. Conformation of the Side Chain of Hopane and Isohopane, and Their Derivatives
- 73(P2-3) シダ植物およびキク科植物から得られた新骨格のトリテルペノイド(ポスター発表の部)
- 90(P04) β-エリスロイジンの合成研究(ポスター発表の部)
- ASYMMETRIC [2+2] PHOTOCYCLOADDITION REACTION OF A CHIRAL DIOXOPYRROLINE TO 2-(TRIMETHYLSILYLOXY)BUTADIENE : CHIRAL SYNTHESIS OF ERYTHRINA ALKALOIDS
- REARRANGEMENT OF 2,3-DIOXO-1,4-OXAZINES TO 4,5-DIOXOOXAZOLES IN THE REACTION WITH DIMETHYLSULFOXONIUM METHYLIDE
- Chiral Synthesis of Erythrina Alkaloids. I. Total Synthesis of (+)-Erysotrine via Asymmetric Diels-Alder Reaction under High Pressure
- Synthesis of Highly Deydrogenated Oxoerythrinan Alkaloids, Erytharbine and Crystamidine
- Dioxypyrrolines. LV. Stereochemical Pathway of [2+2]Photocycloaddition Reaction of 4,5-Diethoxycarbonyl-1H-pyrrole-2,3-dione to Cycloalkadienes and Cycloalkenes
- Dioxopyrroline. LIV. Steretchemical Pathway of[2+2]Photocycloaddition Reaction of 4,5-Diethoxycarbonyl-1H-pyrrole-2,3-dione to Acyclic Olefins
- Dioxopyrrolines. LIII.Stereochemical Pathway of [2+2] Photocycloaddition Reaction of 4-Ethoxycarbonyl-5-phenyl-1H-pyrrole-2,3-dione to Cyclic Enol Trimethylsilyl Ethers
- The basic and clinical implications of ABC transporters, Y-box-binding protein-1 (YB-1) and angiogenesis-related factors in human malignancies
- 2. 門脈ガス血症を伴った非閉塞性腸管虚血症(NOMI)の1例(第27回群馬消化器病研究会)
- Synthesis and Reactions of 3,7-Cycloerythrinan : Skeletal Rearrangement of 2,7,8-Trioxoerythrinans to 4-Oxo-4H-pyrido[2,1,-a]isoquinolines
- Synthesis of Erythrina and Related Alkaloids.XXIV. Total Synthesis of Erysotrine from 1,7-Cycloerythrinan Derivatives by the Use of a New 1,2-Carbonyl Transposition Method
- Studies toward Total Synthesis of Non-aromatic Erythring Alkaloids. (6). Synthesis of 8-OXO-γ-erythroidine and 8-Oxo-cycloerythroidine, Isomers of the Natural Alkaloids.
- Studies toward Total Synthesis of Non-aromatic Erythrina Alkaloids. (4). Oxidation of Furan Ring of D-Furanoerythrinans with N-Bromoacetamide
- Sweet Potato Acid Phosphatase Immobilized on Glutaraldehyde-Activated Aminopropyl Controlled-Pore Glass : Activation, Repeated Use and Enzyme Fatigue
- Sweet Potato Acid Phosphatase Immobilized on Glutaraldehyde-Activated Aminopropyl Controlled-Pore Glass : Activation, Repeated Use and Enzyme Fatigue(Miscellameous)
- Dual Pathways to Tubular Morphogenesis of Vascular Endothelial Cells by Human Glioma Cells : Vascular Endothelial Growth Factor/Basic Fibroblast Growth Factor and Interleukin-8
- Angiogenesis Factors
- Co-expression of Thymidine Phosphorylase and Heme Oxygenase-1 in Macrophages in Human Malignant Vertical Growth Melanomas
- Two New Morphinane Alkaloids from Stephania cepharantha HAYATA (Menispermanceae)
- Synthesis of Erythrina and Related Alkaloids. XXX. Photochemical Approach. (1). Synthesis of Key Intermediates to Erythrina Alkaloids by Intermolecular [2+2] Photocycloaddition Followed by 1,3-Shift
- Dioxopyrroline. L. Skeletal Rearrangements of 7-Vinyl-7-trimethylsilyloxy-5-ethoxycarbonyl-1-phenyl-2-azabicyclo[3.2.0]heptane-3,4-diones under Thermal, Basic, and Acidic Conditions
- Solid Dispersions of Benidipine Hydrochloride. II. Investigation of the Interactions among Drug, Polymer and Solvent in Preparations
- Solid Dispersions of Benidipine Hydrochloride. I. Preparations Using Different Solvent Systems and Dissolution Properties
- Lycopodium植物トリテルペノイドの化学分類学的研究
- cis-Hinokiresinol, a Norlignan from Anemarrhena asphodeloides, Inhibits Angiogenic Response in Vitro and in Vivo (Pharmacognosy)
- 1,3-Dimethylisoguaninium, an Antiangiogenic Purine Analog from the Sponge Amphimedon paraviridis
- [2+2] Photocycloaddition Reaction of 5-Arylfuran-2,3-diones to Trimethylsilyloxyethylenes
- Dioxopyrrolines. LXI. Cycloaddition Reaction of 4-Benzoyl-5-ethoxycarbonyl-1-phenyl-1H-pyrrole-2,3-dione with 1,3-Dienes : Competitive Occurrence of Normal and Hetero Diels-Alder Reaction and Claisen Rearrangement of the Hetero Diels-Alder Product
- Total Synthesis of Homoerythrinan Alkaloids, Schelhammericine and 3-Epischelhammericine
- Heparin-binding Epidermal Growth Factor-like Growth Factor: p91 Activation, Induction of Plasminogen Activator/Plasminogen Activator Inhibitor, and Tubular Morphogenesis in Human Microvascular Endothelial Cells
- Brefeldin A Protects Ricin-Induced Cytotoxicity in Human Cancer KB Cell Line, but not in its Resistant Counterpart with Altered Golgi Structures
- Potent inhibition of in vivo angiogenesis and tumor growth by a novel cyclooxygenase-2 inhibitor, enoic acanthoic acid
- Alkaloidal Constituents of the Leaves of Stephania cepharantha Cultivated in Japan : Structure of Cephasugine, a New Morphinane Alkaloid
- Alkaloidal Constituents of the Tubers of Stephania cepharantha Cultivated in Japan : Structure of 3,4-Dehydrocycleanine, a New Bisbenzylisoquinoline Alkaloid
- ZnSe/MgS超格子の励起子発光特性
- Molecular Characterization of a Novel Quinolizidine Alkaloid O-Tigloyltransferase : cDNA Cloning, Catalytic Activity of Recombinant Protein and Expression Analysis in Lupinus Plants
- Biochemical and Partial Molecular Characteization of Bitter and Sweet Forms of Lupinus angustifolius, an Experimental Model for Study of Molecular Regulation of Quinolizidine Alkaloid Biosynthesis
- Evaluation of [^C]SA5845 and [^C]SA4503 for imaging of sigma receptors in tumors by animal PET
- CO_2を造影剤に用いたTIPS により改善を得たII型肝賢症候群の1例
- Three New Sesquiterpenes from the Black Heartwood of Cryptomeria japonica
- A New Abietane and Two Dimeric Abietane Diterpenes from the Black Heartwood of Cryptomeria japonica
- Synthetic Study of Piericidins. II. Synthesis of Piericidin Analogues
- Synthetic Study of Piericidins. I. Synthesis of the Side Chain of Piercidin B_1
- Acceleration of Adipose Conversion of 3T3-L1 Cells by Dextran Sulfate
- Anti-Herpes Simplex Virus Activity of Alkaloids Isolated from Stephania cepharantha
- SF-091-2 IPMNをめぐる諸問題 : 切除例における検討(サージカルフォーラム(91)IPMN-1,第111回日本外科学会定期学術集会)
- PS-210-5 IPMNの切除適応と悪性度,予後について(PS-210 ポスターセッション(210)膵臓:悪性・診断-2,第111回日本外科学会定期学術集会)
- PS-171-7 大腸癌肝転移における治療法の選択(PS-171 ポスターセッション(171)肝臓:手術-1,第111回日本外科学会定期学術集会)
- PS-098-8 進行胆道癌の垂直進展と水平進展に対する外科治療(PS-098 ポスターセッション(98)胆管:悪性-1,第111回日本外科学会定期学術集会)
- キク科植物成分 : 数種の日本産タンポポ亜科植物新鮮根のトリテルペノイド
- Alkaloidal Constituents of Vines of Stephania cepharantha(Natural Medicine Note)
- 臨牀指針 成人間生体肝移植におけるアフェレーシスの意義
- S-3 群馬大学外科の研究から(Zen Itoh Memorial Symposium「消化管運動研究の未来」,シンポジウム,第54回日本平滑筋学会総会)
- 臨牀指針 拡大左葉グラフト生体肝移植門脈吻合における器械吻合の有用性の検討
- PS-119-1 大網を利用した肝組織片充填有茎小腸グラフトの驚異的増殖法の開発(PS-119 基礎-3 (その他),ポスターセッション,第112回日本外科学会定期学術集会)
- PS-149-7 膵癌細胞株におけるgalectin-3 knockdownによる浸潤能の抑制(膵基礎-3(癌幹細胞,浸潤転移),ポスターセッション,第112回日本外科学会定期学術集会)
- PS-146-2 肝外胆管癌におけるEMT(上皮間葉移行)の予後因子としての重要性とそれに基づく治療戦略(PS-146 肝 基礎・その他,ポスターセッション,第112回日本外科学会定期学術集会)
- PS-099-8 外科的切除における胆管断端癌陽性症例に対する戦略および十二指腸乳頭部癌の縮小手術の可能性(PS-099 胆 悪性-3,ポスターセッション,第112回日本外科学会定期学術集会)
- WS-11-11 当科における膵切除後の合併症の予防および発症後の対策(WS-11 ワークショップ(11)膵切除後の周術期および遠隔期合併症とその対策)
- PS-067-6 食道癌におけるTGFBI発現の臨床的意義(PS-067 食道 基礎-3,第112回日本外科学会定期学術集会)
- VSY-3-3 進行食道癌に対する小開胸・胸腔鏡ハイブリッド手術(VSY-3- ビデオシンポジウム(3)進行食道癌に対する手術手技とその成績,第112回日本外科学会定期学術集会)
- PS-086-3 コノフィリンによる肝線維化の抑制(PS ポスターセッション,第113回日本外科学会定期学術集会)
- PS-385-3 門脈血流を考慮した肝組織片充填有茎小腸グラフトの開発(PS ポスターセッション,第113回日本外科学会定期学術集会)
- PS-104-3 胆管癌におけるE/N cadherin functional switchおよびFOXC2発現による浸潤転移機構の解明と臨床病理・臨床予後に関する意義(PS ポスターセッション,第113回日本外科学会定期学術集会)
- VF-076-4 膵良性腫瘍に対する腹腔鏡補助下膵体尾部切除術の工夫(VF ビデオフォーラム,第113回日本外科学会定期学術集会)
- PS-062-6 多臓器転移を有する大腸癌に対する化学療法(PS ポスターセッション,第113回日本外科学会定期学術集会)
- PS-234-3 新規同定されたImmune checkpoint(B7-H3,B7-H4)の膵癌組織における発現とその意義(PS ポスターセッション,第113回日本外科学会定期学術集会)