Studies on Cytotoxic Constituents in Pericarps of Mallotus japonicus. IV

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概要

• 論文の詳細を見る

• Two new phloroglucinol derivatives, isomallotolerin (1) and isomallotochromanol (2), were isolated from the cytotoxic fraction of the pericarps of Mallotus japonicus. The new derivatives were identified as 3-(3-methyl-2-hydroxybut-3-enyl)-5-(3-acetyl-2,4-dihydroxy-5-methyl-6-methoxybenxyl)-phlorisobutyrophenone (1) and 6-acetyl-5,7-dihydroxy-8-(3-acetyl-2,4-dihydroxy-5-methyl-6-methoxybenxyl)-2,2-dimethyl-3-hydroxychroman (2) from chemical and spectral data. Isomallotolerin and its acetate were found to be cytotoxic to KB cell line.

• 社団法人日本薬学会の論文
• 1990-03-25

著者

• 有澤 宗久

  Department of Medicinal Resources, Faculty of Pharmaceutical Sciences, Toyama Medical & Pharmaceutic

• 森田 直賢

  Department of Medicinal Resources, Faculty of Pharmaceutical Sciences, Toyama Medical & Pharmaceutic

• 林 利光

  富山医科薬科大学薬学部

• 林 利光

  Department of Medicinal Resources, Faculty of Pharmaceutical Sciences Toyama Medical & Pharmaceutica

• 藤田 章夫

  Department of Medicinal Resources, Faculty of Pharmaceutical Sciences

• 菊池 徹

  Department of Natural Product Chemistry, Research Institute for Wakan-Yaku (Oriental Medicine)

• 手塚 康弘

  Department of Natural Product Chemistry, Research Institute for Wakan-Yaku (Oriental Medicine)

• 有澤 宗久

  富山医科薬科大学薬学部

• 菊池 徹

  富山医科薬科大学和漢薬研究所化学応用部門

• 森田 直賢

  Department Of Medicinal Resources Faculty Of Pharmaceutical Sciences Toyama Medical & Pharmaceut

• 藤田 章夫

  Department Of Medicinal Resources Faculty Of Pharmaceutical Sciences:toyoma Medical And Pharmaceutic

• 林 利光

  富山医科薬科大学薬学部生薬学教室

• 菊池 徹

  富山医薬大和漢薬研化学応用

• 林 利光

  Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University

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