A Cytotoxic Constituent of Lysimachia japonica THUNB. (Primulaceae) and the Structure-Activity Relationships of Related Compounds

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概要

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• A cytotoxic alkylresorcinol was isolated from Lysimachia japonica THUNB. (Primulaceae) and identified as grevillol (2). t was tested for cytotoxicity against KB, B-16,PC-13,L-5178Y, P-388,and HEp-2 cells in vitro. Synthetic related compounds were also tested for cytotoxicity against the KB cell line, and the structure-activity relationships are discussed.

• 社団法人日本薬学会の論文
• 1989-09-25

著者

• 森田 直賢

  Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University

• 有澤 宗久

  Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University

• 有澤 宗久

  富山医科薬科大学薬学部

• 大村 和伸

  Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University

• 小林 昭雄

  Faculty of Agriculture, Okayama University

• 森田 直賢

  Department Of Medicinal Resources Faculty Of Pharmaceutical Sciences Toyama Medical & Pharmaceut

• 小林 昭雄

  Faculty Of Agriculture Okayama University

• 大村 和伸

  Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University

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