Analysis of Bile Acids and Cholesterol by Open Tubular Glass Capillary-Selected Ion Monitoring

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概要

• 論文の詳細を見る

• A method for the baseline separation of the dimethylethylsilyl (DMES) ether derivatives of bile acid ethyl esters and cholesterol was developed by using selected ion monitoring (SIM) with open tublar glass capillary column coated with SE-30. The DEMS ether derivatives of bile acid ethyl esters were eluted in the regular order according to the number of hydroxyl group in the molecule. The detection limit of the DMES ether derivative of lithocholic acid ethyl ester was 5 pg with S/N ratio at 5 : 1.

• 公益社団法人日本薬学会の論文
• 1978-09-25

著者

• 石橋 正兀

  Research Laboratories, Pharmaceuticals Group, Nippon Kayaku Co., Ltd.,

• 石橋 正兀

  日本化薬(株)医薬事業本部総合研究所

• 宮崎 浩

  寿製薬研究部

• 山下 幸和

  Pharmaceutical Institute Tohoku University

• 山下 幸和

  日本化薬(株)医薬事業本部総合研究所

• 宮崎 浩

  Research Laboratories of Pharmaceuticals Group, Nippon Kayaku Co., Ltd.,

• 石橋 正兀

  Research Laboratories Of Pharmaceuticals Group Nippon Kayaku Co. Ltd.

• 山下 幸和

  Research Laboratories, Pharmaceutical Group, Nippon Kayaku Co.,

• 西川 裕子

  Research Laboratories of Pharmaceutical Division, Nippon Kayaku Co.,

• 西川 裕子

  Research Laboratories Of Pharmaceutical Division Nippon Kayaku Co.

• 山下 幸和

  Research Laboratories Pharmaceutical Group Nippon Kayaku Co.

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