Mass Fragmentographic Determination of 1-Piperidino-2,4'-dimethylpropiophenone (Mydocalm) by Use of 1 : 1 Mixture Technique
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概要
- 論文の詳細を見る
Artificially created cluster technique has been used for the quantitative determination of serum levels of 1-piperidino-2,4'-dimethylpropiophenone (Mydocalm). A mixture of unlabeled drug and stable isotope labeled drug (Mydocalm-^<15>N) was orally administered for identification of Mydocalm. Decadeuterium labeled Mydocalm (Mydocalm-d_<10>) was prepared and used as an internal standard and carrier for determination. A 100 mg dose of Mydocalm has been given orally to 3 subjects.
- 公益社団法人日本薬学会の論文
- 1975-04-25
著者
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石橋 正兀
Research Laboratories, Pharmaceuticals Group, Nippon Kayaku Co., Ltd.,
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宮崎 浩
日本化薬(株)経営企画室
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石橋 正兀
日本化薬(株)医薬事業本部総合研究所
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宮崎 浩
寿製薬研究部
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宮崎 浩
Research Laboratories of Pharmaceuticals Group, Nippon Kayaku Co., Ltd.,
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井津 源市
Research Laboratories of Pharmaceutical Division, Nippon Kayaku Co.
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石橋 正兀
Research Laboratories Of Pharmaceuticals Group Nippon Kayaku Co. Ltd.
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高山 秀樹
Research Laboratorise, Phamaceutical Group, Nippon Kayaku Co. Ltd.,
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伊沢 寿子
Research Laboratories of Pharmaceutical Division, Nippon Kayaku Co.
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伊沢 寿子
Research Laboratories Of Pharmaceutical Division Nippon Kayaku Co.
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井津 源市
Research Laboratories Of Pharmaceutical Division Nippon Kayaku Co.
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高山 秀樹
Research Laboratorise Phamaceutical Group Nippon Kayaku Co. Ltd.
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