Bromination of 3-tert-Butylindoles with N-Bromosuccinimide
スポンサーリンク
概要
- 論文の詳細を見る
Reaction of 3-tert-butylindole (1a) with NBS in acetic acid gave 3-tert-butyloxindole (2a) and 6-bromo-3-tert-butylindole (3a) instead of 2-bromo derivative (5a). Reactions of 1-acetyl-(1b) and 1-tert-butyl-(1c) derivatives under similar conditions gave 3-bromooxindole (6b) and the brominated indole (7) respectively. On the other hand reaction of 1a with NBS in boiling carbon tetrachloride in the presence of benzoyl peroxide gave unstable 5a as a main product. Reaction of 1b under similar condition did not proceed, but 1c gave 7 as a main product.
- 公益社団法人日本薬学会の論文
- 1977-02-25
著者
-
中川 昌子
Faculty of Pharmaceutical Sciences, Chiba University
-
日野 亨
Faculty of Pharmaceutical Sciences, Chiba University
-
中川 昌子
千葉大薬
-
日野 亨
千葉大 薬
-
中川 昌子
Faculty Of Pharmaceutical Sciences Hokkaido University
-
中川 昌子
千葉大 薬
-
石井 庸一
Faculty Of Pharmaceutical Sciences Chiba University
-
殿塚 雅克
Faculty of Pharmaceutical Sciences, Chiba University
-
殿塚 雅克
Faculty Of Pharmaceutical Sciences Chiba University
関連論文
- Enantioselective Reduction of meso-Cyclic-1,2-dicarboxylic Anhydrides and 1,2-Dicarboximides : Asymmetric Synthesis of Bicyclic Lactones and Hydroxylactams
- 12 マンザミンAおよびその関連化合物の全合成(口頭発表の部)
- 102(P26) 光学活性イルシナールAの合成研究(ポスター発表の部)
- 54(P18) 海洋産脂質過酸化抑制インドールアルカロイドMartefragin Aの合成と活性(ポスター発表の部)
- 学術貢献賞受賞 村上泰興氏の業績
- 薬学会賞受賞 池上四郎氏の業績
- "夢"と"ロジック"と"アート"とを
- 日本薬学会功労賞受賞, 古賀直文氏の業績
- Decarboxylative C-S Bond Formation. Synthesis of 1,4-Dimethyl-3,6-epidithio-2,5-piperazinedione and Related Compounds
- Synthesis of 3,6-Diethoxycarbonyl-3,6-epidithia-1,4-dimethyl-2,5-piperazinedione and Related Compounds. Formation of C-S Bond by the Reaction of Carbanion and Sulfur Monochloride
- Oxidation of Benzoyl Methionine to Benzoyl Methionine Sulfoxide with 3-Hydroperoxyindolenines
- Studies on Thioamides. I. Synthesis of N-(2-Arylethyl)-thioamides and their Infrared Absorption Spectra.
- The Reductive Cyclization of 1-Methyl-3-aminoalkyloxindoles with Lithium aluminum Hydride.
- Synthetic Approaches to Calycanthaceae Alkaloids. III. Reductive Cyclization of 3,3'-Bioxindoles. (1). A Formation of 5,7-Dimethyl-11b, 11c-bis (2-dimethylaminoethyl)-5,5a, 6a, 7,11b, 11c-hexahydrofuro [2,3-b : 5,4-b'] diindole.
- Synthetic Approaches to Calycanthaceae Alkaloids. II. A Synthesis of 1,1'-Dimethyl-3,3'-bis (2-aminoethyl)-3,3'-bioxindole.
- Tryptophan環状互変異性体の化学
- 日本薬学会学術賞受賞高野誠一氏の業績
- 第5回日仏医薬・精密化学シンポジウム
- 亀谷哲治教授(前会頭, 星薬科大学長)に国際複素環化学会賞授与さる
- 教養としての第2外国語を(薬学教育における第2外国語教育)
- やりくり苦心談
- 放射線障害防護薬剤に関する研究(第15報)インドール系化合物の放射線障害防護効力について
- 放射線障害防護薬剤に関する研究(第8報)システアミン関連化合物の放射線障害防護効力について
- 放射線障害防護薬剤に関する研究(第7報) : AETおよびその関連化合物の放射線障害防護効力について
- Radiation-Protective Agents. V. Synthesis and Hydrolysis of 2-(2-Aminoethylthio) indole Derivatives
- Radiation-Protective Agents. IV. Synthesis of Tetrahydro-β-carbolines and 2-Aminothiazoline Derivative from Tryptophanols
- Reactivities of Radiation-protective Aminoalkylisothiuronium Salts. IV. Stability of N-Ethyl Derivatives of 2-Aminoethylisothiuronium Salt
- Reactivities of Radiation-protective Aminoalkylisothiuronium Salts. II. Spectrophotometric Studies on the Reductivities of 2-Mercaptoethylamine, 2-Mercaptoethyl-, and 3-Mercaptopropyl-guanidine.
- Radiation-protective Agents. II. The Transformation of 2-(2-Aminoethyl)thiopseudoureas to 2-Amino-2-thiazolines
- Radiation-protective Agents.I. Studies on N-Alkylated-2-(2-aminoethyl)thiopseudoureas and 1,1-(Dithioethylene)diguanidines
- Reactivities of Radiation-protective Aminoalkylisothiuronium Salts. I. Hydrogen Ion Liberation of 2-Aminoethylisothiuronium and 3-Amino-propylisothiuronium Bromide Hydrobromide
- On the Reaction of N, N'-Dimethylfumaranilide with Aluminium Chloride
- 66 2-ピリジノン及び2-キノロン誘導体のDiels-Alder反応ダイナミシンA基本骨格合成への応用(ポスター発表の部)
- The ^1H- and ^C-Nuclear Magnetic Resonance Spectra of Manzamine C and Related Compounds
- Alkylation of 3,4-Dihydro-β-carboline
- 53 海産抗腫瘍性アルカロイドマンザミン類の合成研究(口頭発表の部)
- スフィンゴ糖脂質の合成
- The Pictet-Spengler Reaction of N_b-Hydroxytryptamines and Cysteinals. II. Temperature Effects, Stereochemistry and Mechanism
- Reactions of the Cyclic Tautomer of 3-Indoleacetamides. : Synthesis of N_b-Methyl-4,5,6-tribromo-3-indoleacetamide
- 2-Hydroxy-1-substituted-1,2,3,4-tetrahydro-β-carbolines. : The Pictet-Spengler Reaction of N-Hydroxytryptamine with Aldehydes
- 抗ウイルス性海洋天然物ユ-ディストミンの合成
- 1-(1-Pyrrolin-2-yl)-β-carbolines. Synthesis of Eudistomins H, I, and P
- 19 抗ビールス性海洋天然物ユーデストミンの合成 : Pictet-Spengler反応の新展開(口頭発表の部)
- Synthetic Approaches to Fumitremorgins. III. : Synthesis of Optically Active Pentacyclic Ring Systems, and Their Oxidation at Ring C
- 生体内類似反応によるトリプトファン代謝産物の合成研究
- 61 フミトレモルジンBおよび関連化合物の合成
- Inverted Prenylation of N_b-Methoxycarbonyltryptamine. Synthesis of 3a-(1,1-Dimethylallyl) pyrrolo [2,3-b] indole and 2-(1,1-Dimethylallyl) tryptamine Derivatives
- Cyclic Tautomers of Tryptophans and Tryptamines. VIII. Cyclic Tautomers of cyclo-L-Prolyl-L-tryptophyl and Related Compounds
- 28 フミトレモルジン合成へのアプローチ
- Formation and Reactions of the Cyclic Tautomers of Tryptophans and Tryptamines. VII. Hydroxylation of Tryptophans and Tryptamines
- Synthesis of the Imidazo [1,2-a] indole-spirolactone Ring System by Oxidative Double Cyclization. A Synthetic Approach to Tryptoquivalines
- Cyclic Tautomers of Tryptophans and Tryptamines. VI. Preparation of N_a-Alkyl-, 5-Chloro-, and 5-Nitrotryptophan Derivatives
- 22 Tryptoquivaline類合成へのアプローチ : Double cyclizationによる2,3,3a,4-tetrahydro-1H-imidazo[1,2-a]indole-4-Spiro-5'-γ-butyrolactoneの合成
- 5 ギ酸中でのTryptamine誘導体の増感酸素化反応.rac-Folicanthine,rac-Chimonanthineの合成
- Dye-sensitized Photooxygenation of Tyrptophan : 3a-Hydroperoxypyrroloindole as a Labile Precursor of Formylkynurenine
- Bromination of 2-Bromo, 2-Ethylthio, and 2-Ethylsulfonylindoles with N-Bromosuccinimide. Isolation and Reactions of 1-Bromoindoles and 3-Bromoindolenines
- Reaction of Skatole with Iodine in the Presence of Thiourea
- 2-Indolinethiones. Tautomerism and Oxidation to the Disulfides
- Preparation of 3-Arylindoles
- Preparation of 3-Substituted 2-Indolinethiones via Diindolyl Disulfides. The Reaction of 3-Substituted Indoles with Sulfur Monochloride
- オクテット
- Studies on the Bischler-Napieralski Reaction with Unsaturated Lactams. Syntheses of 5,6,9,10,11,12-Hexahydro-2,3-dimethoxybenzo [4,5-a]-benzo [f] quinolizinium and Dihydrosempervirine Salts
- Halogenation of 1-Substituted Skatoles. Preparation of 3-Bromomethylindoles
- Infrared Spectra of Some Indole and Pyrrole Compounds
- Reaction of 1-Phenethyl-2 (1H)-pyridones with Phosphoryl Chloride. Formation of 1-Phenethyl-2-chloropyridinium Salts.
- 94(P12) 有機金属反応を利用した簡易ケトン合成とダイネミシンAモデル合成への応用(ポスター発表の部)
- P-31 光学活性イルシナール類合成へのアプローチ(ポスター発表の部)
- 有機化学者のための蛋白質過剰生産
- Reaction of Tryptamine and Aniline with δ-Valerolactone and Its Dehydro Derivatives. A New Synthesis of 1,2,3,4,6,7,12,12b-Octahydroindolo [2,3-α] quinolizine
- Bromination of 3-tert-Butylindoles with N-Bromosuccinimide
- 有機化学者のための蛋白質過剰生産
- 抗ウイルス性海洋天然物ユーディストミンの合成
- Pyranoindole and Thiopyranoindole. Oxidative Cyclization of 3-Indolepropanol and 3-Indolepropanethiol with N-Bromosuccinimide, N-Chlorosuccinimide, and Singlet Oxygen
- SYNTHESIS OF (±)-FLUSTRAMINE B, A MARINE ALKALOID
- The Fragmentation of Some Oxindoles and 2-Indolinethiones induced by Electron Impact
- Thiation of Oxindoles
- The Acetylation of 3-Acylindoles
- Indole誘導体の光増感酸素化反応--Tryptophanおよび関連化合物を中心として (天然物化学′80A)
- インド-ル環の反応性--3位側鎖の関与する反応を中心として (現代の生命化学--トリプトファンをめぐって)
- インドール誘導体と酸素分子との反応 : 合成化学と生命化学への貢献を心掛けて
- インドール系化合物の光増感酸素化反応について
- 2-インドリンチオンの化学
- Bromination of Skatole. A Simple Preparation of 3-Methyloxindole and 2-Bromo-3-methylindole.