Synthetic Approaches to Calycanthaceae Alkaloids. III. Reductive Cyclization of 3,3'-Bioxindoles. (1). A Formation of 5,7-Dimethyl-11b, 11c-bis (2-dimethylaminoethyl)-5,5a, 6a, 7,11b, 11c-hexahydrofuro [2,3-b : 5,4-b'] diindole.
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概要
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The Ladenburg reduction and lithium aluminium hydride reduction of 3,3'-disubstituted 3,3'-bioxindole were carried out. By the former method, (I) and (II) gave 1,3-dimethylindole and 1-methyl-3-(2-aminoethyl) indole respectively, while by the latter method, (I) gave furo [2,3-b : 5,4-b'] diindoles (XVIII, XXV). The compound (XXVII), which has the same planar structure as the product (XIX) obtained from folicanthine, was obtained by the lithium aluminium hydride reduction of (III).
- 社団法人日本薬学会の論文
- 1961-12-25
著者
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日野 亨
Faculty of Pharmaceutical Sciences, Chiba University
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日野 亨
The Chemical Analysis Center Chiba University:faculty Of Pharmaceutical Sciences Chiba University
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