Synthesis of 5-Pyrazolylbarbituric Acid Derivatives
スポンサーリンク
概要
- 論文の詳細を見る
Diketene reacted with barbituric acids in the presence of the basic catalyst and gave the acetoacetyl derivatives (IV-VI) in excellent yields. Condensation of the 5-acetoacetylbarbituric acids with hydrazine and phenylhydrazine gave the pyrazole (IXa, Xa) and phenylpyrazole derivatives (XIa, XIIa) in quantitative yields, respectively. Intramolecular cyclization of 1,3-dimethyl-5-acetoacetylbarbituric acid in the acidic conditions afforded the γ-pyrone derivative (VIII).
- 公益社団法人日本薬学会の論文
- 1973-12-25
著者
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近藤 嘉和
Pharmaceutical Inst Institute, Tohoku University
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竹本 常松
徳島文理大・薬
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庄子 昇
Pharmaceutical Institute, Tohoku University Aoba-yama, Sendai
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竹本 常松
Pharmaceutical Faculty Tokushima Bunri University
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庄子 昇
Faculty of Pharmaceutical Sciences, Tokushima Bunri University
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庄子 昇
Faculty Of Pharmaceutical Sciences Tokushima Bunri University
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