Particle Size Effects on the Deposition Ratios of Airborne Particles in the Respiratory Tract

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概要

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• Particle size adjusting equipment was manufactured to determine the deposition ratio of airborne particles in the respiratory tract. This equipment is composed of an Andersen low-pressure impactor, one 100l stainless steel tank, two filter holders, one Tedlar bag, one flow meter, and two pumps. We measured deposition ratios of benzo[a]pyrene (BaP) in size-fractionated particles in the respiratory tract using this equipment together with a Hans-Rudolph mask. BaP in particles was extracted using the sonication method and measured with the column concentration HPLC/spectrofluorometric detection method. BaP concentrations in PM0.52 (particles smaller than 0.52 μm) ranged from 0.025 to 0.193 ng/m^3 (CV : 72%), and the CV of deposition ratios of BaP was 23%, (average 44.5%). Furthermore, we measured the deposition ratios of BaP in 6 different sized particles. While high deposition ratios of BaP were observed in PM3.9 air, PM2.5 air, and PM0.76 air, low deposition ratios were found in PM0.52 air, PM0.33 air, and PM0.13 air. We obtained similar results to the theoretical deposition ratio calculated from lung models.

• 公益社団法人日本薬学会の論文
• 2004-04-01

著者

• Goto Sumio

  National Institute for Environmental Studies

• Yajima Hirofumi

  Department of Applied Chemistry, Faculty of Science, Tokyo University of science

• NAKAJIMA Daisuke

  National Institute for Environmental Studies

• GOTO Sumio

  Azabu University

• SUGITA Kazutoshi

  Dia Analysis Service Inc.

• Yajima Hirofumi

  Science University Of Tokyo Faculty Of Science

• Yajima Hirofumi

  Department Of Applied Chemistry Faculty Of Science Science University Of Tokyo

• Nakajima Daisuke

  Research Center For Environmental Risk National Institute For Environmental Studies

• ISHII Tadahiro

  Department of Applied Chemistry, Faculty of Science, Science University of Tokyo

• Ishii Tadahiro

  Science University Of Tokyo Faculty Of Science

• Ishii Tadahiro

  Department Of Applied Chemistry Faculty Of Science Science University Of Tokyo

• Endo Osamu

  National Institute Of Public Health

• Endo Osamu

  Department Of Physics Faculty Of Technology Gunma University

• Goto S

  College Of Environmental Health Azabu University

• Goto S

  Reseacrh Center For Material Cycles And Waste Management National Institute For Environmental Studie

• Sugita Kazutoshi

  Analysis Div. Mitsubishi Chemical Analytech Co. Ltd.

• Endo Osamu

  Department of Environmental Health, National Institute of Public Health

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