Mutagenicity of Suspended Particulate Matter Divided in Three Sizes Indoors
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概要
- 論文の詳細を見る
To clarify indoor air pollution, indoor and outdoor air samples were collected from 22 houses in Tokyo using a low-volume cascade impactor with a quartz fiber filter. Suspended particulate matter (SPM) was classified into three sizes: ≥ 10 μm, 2.5-10 μm and ≤ 2.5 μm. The mutagenic compounds were extracted by the dichloromethane/sonication method. The solution was concentrated by N_2 gas. Mutagenicity was determined by the microsuspension method, employing the Salmonella typhimurium (S. typhimurium) YG 1024 strain in the presence and absence of S9 mix. The samples showed generally higher mutagenicity in the absence of S9 mix than in its presence. Outdoor air tended to have higher or similar mutagenicity to indoor air. The smallest SPM (≤ 2.5 μm) fraction showed the highest mutagenicity (revertants/m^3・air). These results suggest that one of the main sources of high mutagenic SPM indoors is air entering from outdoors.
- 公益社団法人日本薬学会の論文
- 2002-12-01
著者
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NAKAJIMA Daisuke
National Institute for Environmental Studies
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KOHZAKI Ken-ichi
National Institute for Environmental Studies
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GOTO Sumio
Azabu University
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NAKAJIMA Daisuke
Research Center for Environmental Risk, National Institute for Environmental Studies
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TAKAGI Yukihiko
School of Veterinary Medicine, Azabu University
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ENDO Osamu
Department of Physics, Faculty of Technology Gunma University
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Nakajima Daisuke
Research Center For Environmental Risk National Institute For Environmental Studies
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Endo Osamu
Department Of Physics Faculty Of Technology Gunma University
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Goto S
College Of Environmental Health Azabu University
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Goto S
Reseacrh Center For Material Cycles And Waste Management National Institute For Environmental Studie
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Goto Sumio
Research Center For Material Cycles And Waste Management National Institute For Environmental Studie
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Koyano Michiko
Department of Community Environmental Sciences, National Institute of Public Health
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Koyano M
Department Of Community Environmental Sciences National Institute Of Public Health
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Kohzaki Ken-ichi
School of Veterinary Medicine, Azabu University
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Matsushita Hidetsuru
Shizuoka Institute of Environment and Hygiene
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Matsushita H
University Of Shizuoka
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Matsushita H
Graduate School Of Nutritional And Environmental Sciences University Of Shizuoka
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Takagi Yukihiko
School Of Veterinary Medicine Azabu University
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Koyano Michiko
Department Of Community Environmental Sciences National Institute Of Public Health
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Nakajima Daisuke
Research Center for Enviromental Risk National Institute for Environmental Studies
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Endo Osamu
Department of Environmental Health, National Institute of Public Health
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