ビタミンB_6およびグルタチオン関連微生物酵素の触媒機能の解明ならびに応用

概要

論文の詳細を見る
The enzymes concerned with the amine or amino acid metabolisms and glutathione metabolisms were purified, characterized and their genes were clones and analyzed. These enzymes include amine oxidases from Escherichia coli and Aspergillus niger, tyrosine phenol-lyase from Erwinia herbicola, glutathione S-transferase from Issatchenkia orientalis, γ-glutamyltranspeptidase from Escherichia coli. The amine oxidases are useful to assay biogenic amines and the tyrosine phenol-lyase is industrially used to produce L-dopa, a starting material of the medicine for Parkinsonisms. Glutathione S-transferase functioned in the pathway of xenobiotics detoxification. γ-Glutamyltranspeptidase is useful to produce various kinds of γ-glutamyl compounds which may be available as medicines or as nutrients.
日本ビタミン学会の論文
1995-08-25