強磁場下での細胞内骨格再配置のリアルタイム偏光検出 : 生体磁気

概要

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A real-time monitoring system utilizing linearly polarized light was developed for observing intracellular cytoskeleton protein motion and the possible effects of strong static magnetic fields on cell behavior. Smooth muscle cells of a rat were cultured in a petri dish for one day, then were set between a pair of light-polarizing plates, whose polarizing directions were normal to each other and inclined almost 45 degrees against the direction of the magnetic field. The polarized light transmission through the adhering cell layer was measured in real time under magnetic fields of up to 14 T. During the magnetic field exposures, the light transmission increased 50% and reached a stable level within 3 hours. The results indicated that the intracellular cyto-skeleton proteins rotated due to the diamagnetic torque force acting on them.
社団法人日本磁気学会の論文
2002-04-01