放線菌のキシラナーゼ生産におけるInducerとしてのβ-キシロシド, および阻害剤としてのα-キシロシド : キシラナーゼの生産に関する研究(第3報)

概要

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In attempts to obtain effective inducers, a variety of β-D-Xylopyranosides (β-xylosides) including ethyl-, n-propyl-, iso-propyl-, n-butyl-, benzyl-, cyclohexyl-, thiophenyl- and ethylencyanohydrin-β-xylosides were synthesized and tested for inducing activity.Almost all of the β-xylopyranosides possessed more effective inducing activities than xylan. In particular, cyclohexyl-β-xylosides and ethylencyanohydrin-β-xyloside, the most active inducers, had about 50 and 70 times as much effective inducing activity per xylose equivalent as xylan.On the other hand, the induced production of xylanase by methyl-β-xyloside was markedly repressed by the addition of an α-xyloside such as methyl-, ethyl- or iso-propyl-α-xyloside.Furthermore, it appeared that all these inductive β-xylosides as well as the repressive α-xylosides were not hydrolyzed by xylanase nor xylosidase of Streptomyces sp. Thus they were proved to be non-metabolizable effectors.These results seemed to suggest that the inducing activity of certain substances was associated with the presence of a β-D-xylopyranosidic linkage.
社団法人日本生物工学会の論文
1980-03-25