Aspergillus terreusによるサイトカラシンEの生産

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Production of cytochalasin E by Aspergillus terreus. FUJISHIMA, T., M. ICHIKAWA, H. ISHIGE, H.YOSHINO, J. OHISHI, and S. IKEGAMI (Research Laboratory of Yamasa Shoyu Co. Ltd., Choshi : National Institute of Radiological Sciences, Chiba 288) Hokkokogaku 57 : 15-19. 1979. Cytochalasin E was produced by a strain M-120-7 grown on wheat bran. The strain was freshly isolated from soil and was proved to be a new strain of Aspergillus terreus. The solid surface culture on wheat bran (3 kg) was extracted with 50% acetone (33l). The extract was adsorbed on a column of Diaion HP-40 (2.5l), and 6.5 g of almost pure cytochalasin E was obtained upon elution with a linear gradient of acetone from 40% to 100%. For the production of cytochalasin E by A. terreus M-120-7,wheat bran culture was much more effective than liquid and sponge culture with glucose-peptone medium.
社団法人日本生物工学会の論文
1979-01-25