Continuos Production of Acetic Acid Using Immobilized Acetobacter aceti in a Three-Phase Fluidized Bed Bioreactor

概要

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Continuous operation of a three-phase fluidized bed bioreactor using immobilized cells showed that both immobilized and suspended cells contributed to the production of acetic acid. Unlike the rapid decrease in the productivity at dilution rates above 0.25 h^<-1> in the free cell fermentation, the productivity was little affected by the dilution rate in the immobilized cell fermentation. Theoretical models were proposed for the continuous process. The models approximately agreed with the experimental results. Experimental results and/or theoretical caluculations based on the kinetic models showed that suspended cells were important in the production of acetic acid if the solid holdup was small or if gel radius was large. Theoretical calculations showed that an optimal solid holdup or gel size existed at higher dilution rates because of the κ_Lα dependence on solid holdup and particle diameter.
社団法人日本生物工学会の論文
1990-02-25