Oxidation of α-Tocopherol during the Peroxidation of Dilinoleoylphosphatidylcholine in Liposomes
スポンサーリンク
概要
- 論文の詳細を見る
Liposomal suspensions of dilinoleoylphosphatidylcholine (DLPC) containing α-tocopherol (0.1mol%,based on DLPC) were oxidized at 37℃. The oxidation was initiated by a lipid-soluble or water-soluble free radical initiator, or by the addition of CuSO_4 and fructose. In all the oxidation systems, α-tocopherol suppressed the formation of DLPC hydroperoxides until all the α-tocopherol had been depleted. The oxidation products of α-tocopherol were 8a-alkyldioxy-α-tocopherones, 5,6-epoxy-α-tocopherylquinone, 2,3-epoxy-α-tocopherylquinone, and α-tocopherylquinone. The 8a-alkyldioxy-α-tocopherones were decomposed in the liposomes primarily by being hydrolyzed to produce α-tocopherylquinone. The results indicate that α-tocopherol can trap peroxyl radicals to form 8a-alkyldioxy-α-tocopherones which are hydrolyzed to α-tocopherylquinone in phospholipid bilayers. In another oxidation pathway, α-tocopherol may be oxidized by peroxyl radicals to form isomeric epoxy-α-tocopherylquinones.
- 社団法人日本農芸化学会の論文
- 1996-04-23
著者
-
Kato Koji
Department Of Hematology Aomori Prefectural Central Hospital
-
Yamauchi Ryo
Department Of Molecular Chemistry And Engineering Faculty Of Engineering Tohoku University
-
Yamauchi Ryo
Department Of Food Science Faculty Of Agriculture Gifu University
-
YAGI Yuko
Department of Public Health, School of Medicine, Nihon University
-
Yamauchi Ryo
Department Of Applied Life Science Faculty Of Applied Biological Sciences Gifu University
-
Yagi Yuko
Department Of Cardiovascular Surgery And Psychosomatic Medicine Nihon University School Of Medicine
-
Yagi Yuko
Department Of Food Science Faculty Of Agriculture Gifu University
-
Kato Koji
Department Of Applied Life Science Faculty Of Applied Biological Sciences Gifu University
-
Kato Koji
Department Of Food Science Faculty Of Agriculture Gifu University
関連論文
- Studies on tribology
- Peripheral blood stem cell versus bone marrow transplantation from HLA-identical sibling donors in patients with leukemia : a propensity score-based comparison from the Japan Society for Hematopoietic Stem Cell Transplantation registry
- Reconstitution of HLA-A^*2402-Restricted Cytomegalovirus-Specific T-Cells following Stem Cell Transplantation
- Retention but significant reduction of BCR-ABL transcript in hematopoietic stem cells in chronic myelogenous leukemia after imatinib therapy
- BMI-1 Is Highly Expressed in M0-Subtype Acute Myeloid Leukemia
- Outcome of Non-T-Cell-Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation from Family Donors in Children and Adolescents
- Subsequent Products After Antioxidant Actions of β-Carotene and α-Tocopherol Have No Salmonella Mutagenicity(Food & Nutrition Science)
- Current Status of Hematopoietic Cell Transplantation for Adult Patients with Hematologic Diseases and Solid Tumors in Japan
- Clinical evaluation of tocilizumab for patients with active rheumatoid arthritis refractory to anti-TNF biologics : tocilizumab in combination with methotrexate
- Effective and Safe Interferon Treatment for Japanese Patients With Chronic Myelogenous Leukemia Relapse After Bone Marrow Transplantation
- Reduced-Intensity Hematopoietic Stem Cell Transplantation for a Patient with Myelodysplastic Syndrome and Chronic Obstructive Pulmonary Disease
- A new marrow T cell depletion method using anti-CD6 monoclonal antibody-conjugated magnetic beads and its clinical application for prevention of acute graft-vs.-host disease in allogeneic bone marrow transplantation: results of a phase I-II trial
- Excessive Daytime Sleepiness among the Japanese General Population
- Mental Health Status, Shift Work, and Occupational Accidents among Hospital Nurses in Japan
- Analysis of 55 Transplantations from Unrelated Volunteer Donors Facilitated by Tokai Marrow Donor Bank
- Quality of Life in Adult Patients after Bone Marrow Transplantation
- Comparison of the effects of omeprazole and famotidine in treatment of upper abdominal symptoms in patients with reflux esophagitis
- Low-Dose Cyclosporin A with Short-Term Methotrexate for Graft-versus-Host Disease Prophylaxis in Allogeneic Bone Marrow Transplantation from Human Leukocyte Antigen-Identical Siblings : A Prospective Phase II Study in Japanese Patients
- Twenty Years' Experience in Allogeneic Hematopoietic Stem Cell Transplantation for Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia in the Nagoya Blood and Marrow Transplantation Group
- Oxidation Products of β-Carotene during the Peroxidation of Methyl Linoleate in the Bulk Phase
- Unification of Hematopoietic Stem Cell Transplantation Registries in Japan and Establishment of the TRUMP System
- Unrelated Donor Marrow Transplantation for Congenital Immunodeficiency and Metabolic Disease : An Update of the Experience of the Japan Marrow Donor Program
- Sacral Nerve Root Cysts Manifesting as Localized Unilateral Perineal Pain : Case Report
- Effect of Soybean Saponin on Trypsin-Inhibiting Activity of Bowman-Birk Inhibitor
- Effect of Dry-Heated Egg White on Wheat Starch Gel and Gluten Dough
- Freeze-Gelation of Sucrose or Trehalose Treated Soymilk
- Preparation of the Addition Products of α-Tocopherol with Cholesteryl Linoleate-Peroxyl Radicals(Food & Nutrition Science)
- Peroxyl-Radical Reaction of Retinyl Acetate in Solution
- Benzyl Caffeate, an Antioxidative Compound Isolated from Propolis
- Reaction of δ-Tocopherol with an Alkylperoxyl Radical(Food & Nutrition)
- Reaction Products of γ-Tocopherol with an Alkylperoxyl Radical in Benzene(Food & Nutrition)
- Reaction of α-Tocopherol with 2,2'-Azobis (2,4-dimethylvaleronitrile) in Benzene(Food & Nutrition)
- Effect of Metal Salts and Fructose on the Autoxidation of Methyl Linoleate in Emulsions(Food & Nutrition)
- Bitter Principle of Tubers of Sagittaria trifolia (Kuwai)
- Prooxidant Effect of Dihydroxyacetone and Reducing Sugars on the Autoxidation of Methyl Linoleate in Emulsions
- Reaction of 8a-Hydroperoxy Tocopherones with Ascorbic Acid
- Atomic Control of Ultrafine Gold Particles on MgO(100) as Investigated by Molecular Dynamics and Computer Graphics
- Molecular Dynamics Simulations of Metal Clusters and Metal Deposition on Metal Surfaces
- Aluminum Reflow Behavior in Via-Hole Filling Investigated by Molecular Dynamics Simulation and Computer Graphics
- THE INFLUENCE OF ^B ADDITION ON THE SWELLING SUPPRESSION BY PHOSPHORUS AND TITANIUM IN Fe-Cr-Ni
- Preparation and Characterization of 8a-(Phosphatidylcholine-dioxy)-α-tocopherones and their Formation during the Peroxidation of Phosphatidylcholine in Liposomes
- Volatile Components of the Essential Oils in Galanga (Alpinia officinarum Hance) from Vietnam
- Oxidation of α-Tocopherol during the Peroxidation of Dilinoleoylphosphatidylcholine in Liposomes
- Successful Treatment of Diffuse Large B-cell Lymphoma Following Waldenstrom's Macroglobulinemia with CHOP Chemotherapy Followed by Combination Therapy of CHOP with Rituximab
- Changes in Pectic Polysaccharides during the Ripening of Cherry Tomato Fruits
- Purification and Some Properties of Pectinesterase from Fruits of a Miniature-Fruited Red Type Tomato
- Risk Analysis for Depression and Patient Prognosis After Open Heart Surgery
- Early treatment of CMV antigenemia with ganciclovir for prevention of fatal CMV disease in patients receiving marrow from HLA-matched unrelated donors
- Development of a Compact Divertor Simulator Excited by Helicon-Wave Discharge
- Solvent Extraction of Copper(I) and Copper(II) from Aqueous Halide Solutions with Tetrabutylammonium Ions into Chloroform
- HDI-12 FRICTION CONTROL BY MICRO-VIBRATION UNDER MICRO-LOAD FOR MAGNETIC RECORDING STORAGE
- Trough plasma concentration of imatinib reflects BCR-ABL kinase inhibitory activity and clinical response in chronic-phase chronic myeloid leukemia : A report from the BINGO study
- An Antioxidant of Dried Chili Pepper Maintained Its Activity through Postharvest Ripening for 18 Months
- Efficacy of Prophylactic Treatment with Selective Serotonin Reuptake Inhibitors for Depression After Open-Heart Surgery
- A Novel Chemoattractant Lectin, Karatoxin, From the Dorsal Spines of the Small Scorpionfish Hypodytes rubripinnis
- Diagnostic Value of Serum Procalcitonin and C-reactive Protein for Infections after Allogeneic Hematopoietic Stem Cell Transplantation versus Nontransplant Setting
- Association analysis of the NOD2 gene with susceptibility to graft-versus-host disease in a Japanese population
- Excellent outcomes of children with CML treated with imatinib mesylate compared to that in pre-imatinib era
- Development of a Compact Divertor Simulator Excited by Helicon-Wave Discharge
- Excellent outcome of allogeneic bone marrow transplantation for Fanconi anemia using fludarabine-based reduced-intensity conditioning regimen
- Initial low-dose valganciclovir as a preemptive therapy is effective for cytomegalovirus infection in allogeneic hematopoietic stem cell transplant recipients
- Evaluation of the Feasibility and Efficacy of Autologous Stem Cell Transplantation in Elderly Patients with Multiple Myeloma
- Decrease in Venous Irritation by Adjusting the Concentration of Injected Bendamustine
- Effectiveness and Safety of Antiemetic Aprepitant in Japanese Patients Receiving High-Dose Chemotherapy Prior to Autologous Hematopoietic Stem Cell Transplantation
- Preparation of a Perisopropylidene Derivative of Pachymaran
- Monohydroperoxides Formed by Autoxidation and Photosensitized Oxidation of Methyl Eicosapentaenoate
- Myoglobin-catalyzed Peroxidation Products of Methyl Eicosapentaenoate
- Chlorophyll-sensitized Photooxidation Products of Spinach Galactolipids
- Separation and Purification of Molecular Species of Galactolipids by High Performance Liquid Chromatography
- Autoxidation and Photosensitized Oxidation of Methyl Eicosapentaenoate: Secondary Oxidation Products
- Lipoxygenase-catalyzed Oxygenation of Monogalactosyldilinolenoylglycerol in Dipalmitoylphosphatidylcholine Liposomes
- Simple Method for Refining Arabinan Polysaccharides by Alcohol Extraction of the Prune, Prunus domestica L.
- Alkali Extraction of β-D-Glucans from the Sclerotia of Corticium rolfsii
- Alpha-1 Adrenoceptor Subtypes in Canine Aorta.