Effect of Coronary Risk Factors on Coronary Angiographic Morphology in Patients With Ischemic Heart Disease

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概要

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• We investigated the effects of hypercholesterolemia, hypertension, and diabetes mellitus, which are major coronary risk factors, on the angiographic morphology of coronary artery lesions in 204 patients with previous myocardial infarction or stable-effort angina: 39 patients with hypercholesterolemia (serum total cholesterol >240 mg/dl) without hypertension and diabetes, 51 patients with hypertension without diabetes and hypercholesterolemia, 24 patients with diabetes without hypertension and hypercholesterolemia, and 90 patients without any of these 3 risk factors (control). Patients without coronary artery lesions were excluded. The severity of coronary artery lesions is expressed as the Gensini score and the morphology is classified according to Rosch's classification. The distribution of coronary artery lesions did not differ significantly between the 4 groups. The Gensini score was significantly higher in the hypercholesterolemia group than in the other groups (p<0.05). Short concentric lesions were more frequent in the hypercholesterolemia group than in the control group (p<0.01), and tubular regular lesions were more frequent in the hypertension and diabetes groups than in the control group (p<0.01). These results suggest that hypercholesterolemia has a greater influence on the severity of coronary artery lesions than does hypertension or diabetes, and that the progression of coronary atherosclerosis may differ among patients with these risk factors.

• 社団法人日本循環器学会の論文
• 1997-04-20

著者

• Miura Toshiro

  Department Of Medicine And Clinical Science Yamaguchi University Graduate School Of Medicine

• Ogawa Hiroshi

  Division Of Cardiology Tokuyama Central Hospital

• Kawamura K

  Department Of Internal Medicine (iii) Osaka Medical College

• Katayama Kazuhiro

  Department Of Internal Medicine (iii) Osaka Medical College

• Katayama Kazuhiro

  Second Department Of Internal Medicine Yamaguchi University School Of Medicine

• Matsuzaki Masunori

  Second Department of Internal Medicine, Yamaguchi University, School of Medicine

• Miura Toshiro

  Second Department Of Internal Medicine Yamaguchi University School Of Mediciney

• OGAWA HIROSHI

  Second Department of Internal Medicine, Yamaguchi University

• Kasaoka Shunji

  Second Department of Internal Medicine, Yamaguchi University School of Medicine

• Okuda Fumio

  Second Department of Internal Medicine, Yamaguchi University School of Medicine

• Satoh Akira

  Second Department of Internal Medicine, Yamaguchi University School of Medicine

• Kohno Michihiro

  Second Department of Internal Medicine, Yamaguchi University School of Medicine

• Fujii Takashi

  Second Department of Internal Medicine, Yamaguchi University School of Medicine

• Matsuzaki Masunori

  Second Department Of Internal Medicine Yamaguchi University School Of Medicine

• Okuda Fumio

  Second Department Of Internal Medicine Yamaguchi University School Of Medicine

• Kohno Michihiro

  Division Of Cardiovascular Medicine Department Of Medical Bioregulation Yamaguchi University Graduat

• Kohno Michihiro

  Second Department Of Internal Medicine Yamaguchi University School Of Medicine

• Kohno Michihiro

  Second Division Department Of Internal Medicine Yamaguchi University

• Ogawa Hiroshi

  Division Of Cardiovascular Medicine Department Of Medical Bioregulation Yamaguchi University School

• Miyazaki Tsuyoshi

  Department Of Rheumatology Sagamihara National Hospital National Hospital Organization (nho)

• Fujii Takasi

  The Second Depertment Of Internal Medicine

• Fujii Takashi

  Second Department Of Internal Medicine Yamaguchi University School Of Medicine

• Satoh Akira

  Second Department Of Internal Medicine Yamaguchi University School Of Medicine

• Fujii Takashi

  Second Department Of Internal Medicine Yamaguchi University Of Medicine

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