Neurotoxins, 1-methy1-4-phenyl-1, 2, 3, 6-tetrahydropyridine, 1, 2, 3, 4, -tetrahydroisoquinoline, N-methyl-tetrahydroisoquinoline and 1-benzyl-tetrahydroisoquinoline, are substrates for rat liver flavin-containing monooxygenase(FMO) expressed in yeast
スポンサーリンク
概要
- 論文の詳細を見る
- 日本トキシコロジー学会の論文
- 1993-11-25
著者
-
Itoh K
Division Of Oncology And Hematology National Cancer Center Hospital East
-
Itoh S
Division Of Bio-medical And Immunological Chemistry Faculty Of Pharmaceutical Sciences Osada Univers
-
Kamataki T
Division Of Drug Metabolism Faculty Of Pharmaceutical Sciences Hokkaido University
-
Chiba K
Division of Clinical Pharmacology, Clinical Research Insutitute, National Medical Center
-
Kimura T
Sandoz Pharmaceuticals
関連論文
- Extreme eosinophilia caused by interleukin-5-producing disseminated colon cancer
- Phase I and II pharmacokinetic and pharmacodynamic study of the proteasome inhibitor bortezomib in Japanese patients with relapsed or refractory multiple myeloma
- Clonal Analysis of Bilateral, Recurrent, or Systemically Multifocal Ocular Adnexal Lymphoma
- Studies on Thermophile Products. X. Further Biological Properties of Isofatty Acid-Containing Phosphatidylglycerol That Enhances the Induction of Suppressor T Cells
- Studies on Thermophile Products. IX. Isofatty Acid-Containing Phosphatidylglycerol That Enhances the Induction of Concanavalin A-Activated Suppressor T Cells
- Studies on Thermophile Products. VIII. Isolation of Bacillus stearothermophilus UBT8038,a Component That Inhibits Antigen Presentation on Mouse Macrophages
- Inhibitory Effect of Tuna Peptide on Endothelin Production in Cultured Endothelial Cells
- Studies on Thermophile Products. VII. Effect of 1,3-Di-14-methylpentadecanoyl Glycerol and Its Related Isofatty Acids on T Cell Proliferation in Vitro
- Prognostic analysis and a new risk model for Hodgkin lymphoma in Japan
- Phase I Study of Intravenous PSC-833 and Doxorubicin: Reversal of Multidrug Resistance
- STUDIES ON PHARMACOLOGICAL ACTIVATION OF HUMAN SERUM IgG BY CHEMICAL MODIFICATION AND ACTIVE SUBFRAGMENTS. V. MECHANISM OF ANTI-INFLAMMATORY ACTION OF CARBOXAMIDE-METHYLATED L-CHAIN (Fr. I-L) AND H-CHAIN (Fr. I-H) FROM HUMAN SERUM IgG.
- Severe hypogammaglobulinemia persisting for 6 years after treatment with rituximab combined chemotherapy due to arrest of B lymphocyte differentiation together with alteration of T lymphocyte homeostasis
- Acquired hemophilia A with sigmoid colon cancer : successful treatment with rituximab followed by sigmoidectomy
- A retrospective analysis of bortezomib therapy for Japanese patients with relapsed or refractory multiple myeloma : β2-microglobulin associated with time to progression
- Dose Modification of Imatinib by Monitoring the Level of BCR-ABL Transcript in Chronic Myelogenous Leukemia
- Increased Expression of Insulin-Like Growth Factor I is Associated with Ara-C Resistance in Leukemia
- Imatinib Mesylate in Conjunction with Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Philadelphia Chromosome Positive Leukemias : Report of 4 Cases
- Detection of Clone-Specific Immunoglobulin Heavy Chain Genes in the Bone Marrow of B-cell-Lineage Lymphoma after Treatment
- High Expression of YB-1 Gene in Erythroid Cells in Patients with Refractory Anemia
- Phase I study of radioimmunotherapy with an anti-CD20 murine radioimmunoconjugate (^Y-ibritumomab tiuxetan) in relapsed or refractory indolent B-cell lymphoma
- Phase 1/2 clinical study of dasatinib in Japanese patients with chronic myeloid leukemia or Philadelphia chromosome-positive acute lymphoblastic leukemia
- Japanese phase II study of ^Y-ibritumomab tiuxetan in patients with relapsed or refractory indolent B-cell lymphoma
- Case-control study of leukemia and diagnostic radiation exposure
- Phase III Study of Ranimustine, Cyclophosphamide, Vincristine, Melphalan, and Prednisolone (MCNU-COP/MP) versus Modified COP/MP in Multiple Myeloma : A Japan Clinical Oncology Group Study, JCOG 9301
- Randomized phase II study of concurrent and sequential rituximab and CHOP chemotherapy in untreated indolent B-cell lymphoma
- Phenotypic analysis of peripheral T/NK cell lymphoma : Study of 408 Japanese cases with special reference to their anatomical sites
- Morphological spectrum of cyclin D1-positive mantle cell lymphoma : Study of 168 cases
- Population pharmacokinetics of docetaxel in patients with hepatic dysfunction treated in an oncology practice
- Pharmacokinetics and pharmacodynamics of protein-unbound docetaxel in cancer patients
- Extragonadal germ cell tumors in Japan
- Treatable Subsets in Cancer of Unknown Primary Origin
- Toxicity and efficacy of ifosfamide, carboplatin and etoposide (modified ICE) as a salvage chemotherapy in Japanese patients with relapsed or refractory aggressive non-Hodgkin's lymphoma
- Recurrent Breast Cancer Treated Successfully with Mitomycin-C and Vinblastine after Failure of Both Doxorubicin-containing Regimen and Paclitaxel : A Case Report
- A Limited Sampling Model for Estimating Pharmacokinetics of CPT-11 and Its Metabolite SN-38
- Pharmacological Correlation between Total Drug Concentration and Lactones of CPT-11 and SN-38 in Patients Treated with CPT-11
- Sensitive immunohistochemical detection of WT1 protein in tumors with anti-WT1 antibody against WT1 235 peptide
- Safety and efficacy of rasburicase (SR29142) in a Japanese phase II study
- Fludarabine- and Cyclophosphamide-Based Nonmyelobalative Conditioning Regimen for Transplantation of Chronic Granulomatous Disease : Possible Correlation with Prolonged Pure Red Cell Aplasia
- Microbial Serine Carboxypeptidase Inhibitors : Comparative Analysis of Actions on Homologous Enzymes Derived from Man, Yeast and Wheat
- Studies on Biological Activities of Melanin from Marine Animals. V. : Anti-inflammatory Activity of Low-Molecular-Weight Melanoprotein from Squid (Fr. SM II)(Biological)
- Clinical, biochemical, and cytochemical studies on a Japanese Salla disease case associated with a renal disorder
- Tuna Muscle Peptide, PTHIKWGD, Inhibits Leukocyte-Mediated Injury and Leukocyte Adhesion to Cultured Endothelial Cells
- Increase of Cytochrome b mRNA by Bis(2-hydroxyethyl) Trisulfide in J774A.1 Cells
- Studies on Pharmacological Activation of Human Serum Immunoglobulin G(IgG) by Chemical Modification and Active Subfragments. VII. Effect of Carboxamidemethylated Fc(CM-Fc) Fragment from Human Serum IgG on Lymphocytes and Macrophages(Pharmacological,Chemic
- Studies on Pharmacological Activation of Human Serum Immunoglobulin G(IgG) by Chemical Modification and Active Subfragments. VI. Anti-allergic Activity of Carboxamidemethylated Fc(CM-Fc) Fragment from Human Serum IgG(Pharmacological,Chemical)
- Inhibitory Effect of Bis[2-(E-2-octenoylamino)ethyl] Disulfide and 2-(E-Octenoylamino)ethyl Carbamoylmethyl Sulfide on Various Inflammation Models(Biological,Chemical)
- Inhibitory Effect of Bis[2-(E-2-alkenoylamino)ethyl] Disulfides and 2-(E-Octenoylamino)ethyl Carbamoylmethyl Sulfides on Carrageenin-Induced Paw Edema in Rats(Biological,Chemical)
- Photo-Induced Reactions of Oxime O-Ethers Derived from 3-Acyl-1, 2-dihydrocinnoline- 1, 2-dicarboximides
- Novel Photo-Rearrangement of Oxime Methyl Ethers of 3-Acyl-1, 2dihydrocinnoline-N-phenyl-1, 2-dicarboximides
- Positron Emission Tomography/Computed Tomography after Immunocytochemical and Clonal Diagnosis of Intraocular Lymphoma with Vitrectomy Cell Blocks
- Phase II study of oral fludarabine in combination with rituximab for relapsed indolent B-cell non-Hodgkin lymphoma
- Phase I/II and pharmacokinetic study of cladribine with 2-h infusion in Japanese patients with relapsed indolent B-cell lymphoma mostly pretreated with rituximab
- C-C Bond Cleavage of Cyclohexene Oxide in the Reaction with 1-Aminoindoline
- Serum soluble interleukin-2 receptor level and immunophenotype are prognostic factors for patients with diffuse large B-cell lymphoma
- Frequent downregulation or loss of CD79a expression in plasma cell myelomas : Potential clue for diagnosis
- Correlation Between Histological Evaluation and PCR-based Clonality Analysis of Gastric MALT Lymphomas Treated by Eradication of Helicobacter pylori
- Immunoglobulin G4 (IgG4)-Positive or -Negative Ocular Adnexal Benign Lymphoid Lesions in Relation to Systemic Involvement
- Phase I study of the oral mammalian target of rapamycin inhibitor everolimus (RAD001) in Japanese patients with relapsed or refractory non-Hodgkin lymphoma
- Phase II study of ABVd therapy for newly diagnosed clinical stage II-IV Hodgkin lymphoma : Japan Clinical Oncology Group study (JCOG 9305)
- Randomized phase II study of concurrent and sequential combinations of rituximab plus CHOP (cyclophosphamide, doxorubicin, vincristine and prednisolone) chemotherapy in untreated indolent B-cell non-Hodgkin lymphoma : 7-year follow-up results
- Multicenter phase II study of bendamustine for relapsed or refractory indolent B-cell non-Hodgkin lymphoma and mantle cell lymphoma
- BAFF-R is Expressed on B-cell Lymphomas Depending on their Origin, and its Related to Proliferation Index of Nodal Diffuse Large B-cell Lymphomas
- Comparison of Long-Term Clinical Outcomes of CHOP Chemotherapy between Japanese Patients with Nodal Peripheral T-Cell Lymphomas and Those with Diffuse Large B-Cell Lymphoma in the Study Group of the Tohoku Hematology Forum
- Bilateral Conjunctival Lesions in Blastic Plasmacytoid Dendritic Cell Neoplasm
- Clinicopathological Features of Malignant Lymphoma in Japan : The Miyagi Study
- Relevance of monitoring metabolic reduction in patients with relapsed or refractory follicular and mantle cell lymphoma receiving bendamustine : a multicenter study
- Lack of non-hematological cross intolerance of dasatinib to imatinib in imatinib-intolerant patients with Philadelphia chromosome positive chronic myeloid leukemia or acute lymphatic leukemia : a retrospective safety analysis
- Direct antiglobulin test-negative autoimmune hemolytic anemia associated with HLA-haploidentical stem cell transplantation
- Use of mycophenolate mofetil in patients received allogeneic hematopoietic stem cell transplantation in Japan
- Successful treatment with nilotinib after imatinib failure in a CML patient with a four-way Ph chromosome translocation and point mutations in BCR/ABL gene
- Neurotoxins, 1-methy1-4-phenyl-1, 2, 3, 6-tetrahydropyridine, 1, 2, 3, 4, -tetrahydroisoquinoline, N-methyl-tetrahydroisoquinoline and 1-benzyl-tetrahydroisoquinoline, are substrates for rat liver flavin-containing monooxygenase(FMO) expressed in yeast
- Rituximab monotherapy with eight weekly infusions for relapsed or refractory patients with indolent B cell non-Hodgkin lymphoma mostly pretreated with rituximab : A multicenter phase II study
- Local Recurrence as Immunoglobulin G4 (IgG4)-Related Disease 10 Years after Radiotherapy to Ocular Adnexal Extranodal Marginal Zone B-Cell Lymphoma of Mucosa-Associated Lymphoid Tissue
- Strategy for bone marrow transplantation in eculizumab-treated paroxysmal nocturnal hemoglobinuria
- Diagnosis of Intestinal Graft-versus-Host Disease and Thrombotic Microangiopathy after Allogeneic Stem Cell Transplantation
- Orbital MALT Lymphoma, Abdominal Hodgkin lymphoma, and Systemic Diffuse Large B-cell Lymphoma Develop Sequentially in One Patient
- Feasibility of unmanipulated haploidentical stem cell transplantation using standard GVHD prophylaxis for HLA-homozygous patients
- Phase II study of cyclophosphamide, doxorubicin, vincristine, prednisolone (CHOP) therapy for newly diagnosed patients with low-and low-intermediate risk, aggressive non-Hodgkin's lymphoma : final results of the Japan Clinical Oncology Group Study, JCOG95