Local Recurrence as Immunoglobulin G4 (IgG4)-Related Disease 10 Years after Radiotherapy to Ocular Adnexal Extranodal Marginal Zone B-Cell Lymphoma of Mucosa-Associated Lymphoid Tissue
スポンサーリンク
概要
- 論文の詳細を見る
In 2000, a 48-year-old woman developed a left orbital mass with lacrimal gland involvement and then, in 2003, a right orbital mass with lacrimal gland involvement, both of which were diagnosed as extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma). She underwent 30 Gy external beam radiation to bilateral orbital lesions. The lymphoma cells in both lesions did not share the same clonality, as shown by amplification by polymerase chain reaction of the immunoglobulin heavy chain gene. Immunoglobulin light chain analysis by immunohistochemistry and messenger RNA in situ hybridization showed λ chain monotype in the left orbital lesion but κ chain monotype in the right orbital lesion. She developed recurrent left orbital mass with high uptake on fluorodeoxyglucose positron emission tomography fused with computed tomography in 2010, and excisional biopsy disclosed the formation of follicles and infiltration with immunoglobulin G4 (IgG4)-positive plasma cells mainly in interfollicular areas. The immunoglobulin light chain analysis showed the λ chain and κ chain bitype. With the immunohistopathological diagnosis of IgG4-related disease, the serum IgG4 level was found to show elevation at 376 mg/dL, and the patient chose observation. This is the first reported case of development of IgG4-related disease after bilataral orbital MALT lymphoma with external beam radiotherapy. [J Clin Exp Hematopathol 51(2) : 125-133, 2011]
- 2011-11-01
著者
-
Itoh K
Division Of Oncology And Hematology National Cancer Center Hospital East
-
Itoh Kuniaki
神戸大学 医学研究科腫瘍内科学
-
Ichimura Koichi
Department Of Hematology And Rheumatology Tohoku University Graduate School Of Medicine
-
Ishizawa Kenichi
東北大学 血液･免疫病学分野
-
Ishizawa K
Department Of Rheumatology And Hematology
-
Morito Toshiaki
Department Of Pathology Okayama University Graduate School Of Medicine Dentistry And Pharmaceutical
-
Itoh Kuniaki
Hematology And Oncology Division National Cancer Center Hospital East
-
Itoh Kuniaki
Department Of Chemistry Faculty Of Science Kobe University
-
Kawase Ichiro
大阪大学 医学系研究科機能診断科学
-
Ichimura Koichi
Department Of Pathology Okayama University Graduate School Of Medicine Dentistry And Pharmaceutical
-
Ichimura Koichi
Department Of Pathology Okayama University Graduate School Of Medicine And Dentistry
-
Yoshida Takashi
Department Of Hematology Japanese Red Cross Nagoya First Hospital
-
Ichimura Koichi
Department Of Pathology And Molecular Diagnostics Aichi Cancer Center
-
Ichimura Kouichi
Department Of Pathology Okayama University Medical School And Graduate School Of Medicine Dentistry
-
Ichimura Kouichi
Department Of Pathology Okayama University Graduate School Of Medicine Dentistry And Pharmaceutical
-
Yoshino Tadashi
Department Of Pathology Okayama University Graduate School Of Medicine Dentistry And Pharmaceutical
-
Yoshino Tadashi
Department Of Pathology Okayama University
-
Yoshino Tadashi
Department Of Hematology Okayama Rosai Hospital
-
Tamada Yasuhiko
Department Of Dermatology Aichi Medical University Hospital
-
Yoshida T
Tohoku Univ. Sendai Jpn
-
Matsuo Toshihiko
Department Of Communications And Integrated Systems Tokyo Institute Of Technology
-
Matsuo Toshihiko
Department Of Ophthalmology Okayama University Graduate School Of Medicine Dentistry And Pharmaceuti
-
Yoshino Tadashi
Department Of Pathology Okayama University Graduate School Of Medicine Dentistry And Pharmaceutical
-
Yoshino Tadashi
Department Of Pathology Okayama University Graduate School Of Medicine Dentistry And Pharmaceutical
-
Ichimura Koichi
Department Of Pathology Okayama University Medical School And Graduate School Of Medicine Dentistry
-
Yoshino Tadashi
Department Of Cytopathology Ayabe City Hospital
-
Itoh Kuniaki
Division of Hematology and Oncology, National Cancer Center Hospital East
-
Yoshino Tadashi
Department of Chemical Engineering, Hiroshima University
関連論文
- Extreme eosinophilia caused by interleukin-5-producing disseminated colon cancer
- Phase I and II pharmacokinetic and pharmacodynamic study of the proteasome inhibitor bortezomib in Japanese patients with relapsed or refractory multiple myeloma
- Clonal Analysis of Bilateral, Recurrent, or Systemically Multifocal Ocular Adnexal Lymphoma
- Different Kinetics of WT1 and PML-RARα Gene Expression Levels during Remission Induction Therapy with All-trans Retinoic Acid Alone in Acute Promyelocytic Leukemia
- Monitoring Minimal Residual Disease in Leukemia Using Real-time Quantitative Polymerase Chain Reaction for Wilms Tumor Gene (WT1)
- Lethal Adenovirus Infection in a Patient Who Had Undergone Nonmyeloblative Stem Cell Transplantation
- Prognostic analysis and a new risk model for Hodgkin lymphoma in Japan
- Phase I Study of Intravenous PSC-833 and Doxorubicin: Reversal of Multidrug Resistance
- Severe hypogammaglobulinemia persisting for 6 years after treatment with rituximab combined chemotherapy due to arrest of B lymphocyte differentiation together with alteration of T lymphocyte homeostasis
- Acquired hemophilia A with sigmoid colon cancer : successful treatment with rituximab followed by sigmoidectomy
- A retrospective analysis of bortezomib therapy for Japanese patients with relapsed or refractory multiple myeloma : β2-microglobulin associated with time to progression
- Dose Modification of Imatinib by Monitoring the Level of BCR-ABL Transcript in Chronic Myelogenous Leukemia
- Increased Expression of Insulin-Like Growth Factor I is Associated with Ara-C Resistance in Leukemia
- Imatinib Mesylate in Conjunction with Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Philadelphia Chromosome Positive Leukemias : Report of 4 Cases
- Detection of Clone-Specific Immunoglobulin Heavy Chain Genes in the Bone Marrow of B-cell-Lineage Lymphoma after Treatment
- High Expression of YB-1 Gene in Erythroid Cells in Patients with Refractory Anemia
- Separation of antileukemic effects from graft-versus-host disease in MHC-haploidentical murine bone marrow transplantation : participation of host immune cells
- Phase I study of radioimmunotherapy with an anti-CD20 murine radioimmunoconjugate (^Y-ibritumomab tiuxetan) in relapsed or refractory indolent B-cell lymphoma
- Phase 1/2 clinical study of dasatinib in Japanese patients with chronic myeloid leukemia or Philadelphia chromosome-positive acute lymphoblastic leukemia
- Japanese phase II study of ^Y-ibritumomab tiuxetan in patients with relapsed or refractory indolent B-cell lymphoma
- Case-control study of leukemia and diagnostic radiation exposure
- Phase III Study of Ranimustine, Cyclophosphamide, Vincristine, Melphalan, and Prednisolone (MCNU-COP/MP) versus Modified COP/MP in Multiple Myeloma : A Japan Clinical Oncology Group Study, JCOG 9301
- Randomized phase II study of concurrent and sequential rituximab and CHOP chemotherapy in untreated indolent B-cell lymphoma
- Phenotypic analysis of peripheral T/NK cell lymphoma : Study of 408 Japanese cases with special reference to their anatomical sites
- Correlation Between Histological Evaluation and PCR-based Clonality Analysis of Gastric MALT Lymphomas Treated by Eradication of Helicobacter pylori
- Follicular lymphoma frequently originates in the salivary gland
- p27^ is Detected on Most Gastric MALT Lymphomas, but not Large Cell Lymphomas
- Morphological spectrum of cyclin D1-positive mantle cell lymphoma : Study of 168 cases
- Pregnancy-Associated Cytotoxic Lymphoma: A Report of 4 Cases
- Peripheral T/Natural Killer - Cell Lymphoma Involving the Female Genital Tract: A Clinicopathologic Study of 5 Cases
- Population pharmacokinetics of docetaxel in patients with hepatic dysfunction treated in an oncology practice
- Pharmacokinetics and pharmacodynamics of protein-unbound docetaxel in cancer patients
- Extragonadal germ cell tumors in Japan
- Treatable Subsets in Cancer of Unknown Primary Origin
- Toxicity and efficacy of ifosfamide, carboplatin and etoposide (modified ICE) as a salvage chemotherapy in Japanese patients with relapsed or refractory aggressive non-Hodgkin's lymphoma
- Recurrent Breast Cancer Treated Successfully with Mitomycin-C and Vinblastine after Failure of Both Doxorubicin-containing Regimen and Paclitaxel : A Case Report
- A Limited Sampling Model for Estimating Pharmacokinetics of CPT-11 and Its Metabolite SN-38
- Pharmacological Correlation between Total Drug Concentration and Lactones of CPT-11 and SN-38 in Patients Treated with CPT-11
- Unmanipulated Reduced-Intensity Stem Cell Transplantation from a Haploidentical Donor Mismatched at 3 HLA Antigens to a Patient with Leukemic Transformation of Myelodysplastic Syndrome : Successful Second Transplantation after Graft Rejection
- Sensitive immunohistochemical detection of WT1 protein in tumors with anti-WT1 antibody against WT1 235 peptide
- High frequencies of less differentiated and more proliferative WT1-specific CD8^+ T Cells in bone marrow in tumor-bearing patients : An important role of bone marrow as a secondary lymphoid organ
- Safety and efficacy of rasburicase (SR29142) in a Japanese phase II study
- Biased usage of BV gene families of T-cell receptors of WT1 (Wilms' tumor gene)-specific CD8^+ T cells in patients with myeloid malignancies
- Use of foscarnet for cytomegalovirus infection after allogeneic hematopoietic stem cell transplantation from a related donor
- Overexpression of the Wilms' tumor gene WT1 in pancreatic ductal adenocarcinoma
- Fludarabine- and Cyclophosphamide-Based Nonmyelobalative Conditioning Regimen for Transplantation of Chronic Granulomatous Disease : Possible Correlation with Prolonged Pure Red Cell Aplasia
- Different Histopathological Types of Orbital Lymphoma 16 Years after Systemic Follicular Lymphoma : Immunohistochemical and Immunogenetic Analyses of Two Cases
- Microbial Serine Carboxypeptidase Inhibitors : Comparative Analysis of Actions on Homologous Enzymes Derived from Man, Yeast and Wheat
- Patients with localized primary non-tonsillar oral diffuse large B-cell lymphoma exhibit favorable prognosis despite a non-germinal center B-cell-like phenotype
- Impact of Cytogenetics on Outcome of Stem Cell Transplantation for Acute Myeloid Leukemia in First Remission : A Large-Scale Retrospective Analysis of Data from the Japan Society for Hematopoietic Cell Transplantation
- Clinical, biochemical, and cytochemical studies on a Japanese Salla disease case associated with a renal disorder
- Overexpression of the Wilms' tumor gene WT1 in primary thyroid cancer
- Wilms Tumor Gene WT1 Peptide-Based Immunotherapy Induced a Minimal Response in a Patient with Advanced Therapy-Resistant Multiple Myeloma
- WT1_, a Ninemer Peptide Derived from Wilms' Tumor Gene Product, Is a Candidate Peptide for the Vaccination of HLA-A^*0201-Positive Patients with Hematopoietic Malignancies
- Successful Treatment of Tacrolimus (FK506)-Related Leukoencephalopathy with Cerebral Hemorrhage in a Patient Who Underwent Nonmyeloablative Stem Cell Transplantation
- WT1 Peptide-Based Immunotherapy for Patients with Lung Cancer : Report of Two Cases
- Wilms Tumor Gene Peptide-Based Immunotherapy for Patients with Overt Leulemia from Myelodysplastic Syndrome (MDS) or MDS with Myelofibrosis
- The lck Promoter-Driven Expression of the Wilms Tumor Gene WT1 Blocks Intrathymic Differentiation of T-Lineage Cells
- Photo-Induced Reactions of Oxime O-Ethers Derived from 3-Acyl-1, 2-dihydrocinnoline- 1, 2-dicarboximides
- Novel Photo-Rearrangement of Oxime Methyl Ethers of 3-Acyl-1, 2dihydrocinnoline-N-phenyl-1, 2-dicarboximides
- IgG4-producing marginal zone B-cell lymphoma
- Positron Emission Tomography/Computed Tomography after Immunocytochemical and Clonal Diagnosis of Intraocular Lymphoma with Vitrectomy Cell Blocks
- Phase II study of oral fludarabine in combination with rituximab for relapsed indolent B-cell non-Hodgkin lymphoma
- Phase I/II and pharmacokinetic study of cladribine with 2-h infusion in Japanese patients with relapsed indolent B-cell lymphoma mostly pretreated with rituximab
- Pulmonary Coccidioidomycosis That Formed a Fungus Ball with 8-years Duration
- Serum soluble interleukin-2 receptor level and immunophenotype are prognostic factors for patients with diffuse large B-cell lymphoma
- Frequent downregulation or loss of CD79a expression in plasma cell myelomas : Potential clue for diagnosis
- Ocular adnexal IgG4-related disease has uniform clinicopathology
- Spontaneous Regression of Bilateral Conjunctival Extranodal Marginal Zone B-cell Lymphoma of Mucosa-Associated Lymphoid Tissue
- Correlation Between Histological Evaluation and PCR-based Clonality Analysis of Gastric MALT Lymphomas Treated by Eradication of Helicobacter pylori
- Immunoglobulin G4 (IgG4)-Positive or -Negative Ocular Adnexal Benign Lymphoid Lesions in Relation to Systemic Involvement
- Phase I study of the oral mammalian target of rapamycin inhibitor everolimus (RAD001) in Japanese patients with relapsed or refractory non-Hodgkin lymphoma
- Phase II study of ABVd therapy for newly diagnosed clinical stage II-IV Hodgkin lymphoma : Japan Clinical Oncology Group study (JCOG 9305)
- Randomized phase II study of concurrent and sequential combinations of rituximab plus CHOP (cyclophosphamide, doxorubicin, vincristine and prednisolone) chemotherapy in untreated indolent B-cell non-Hodgkin lymphoma : 7-year follow-up results
- Multicenter phase II study of bendamustine for relapsed or refractory indolent B-cell non-Hodgkin lymphoma and mantle cell lymphoma
- Identification of a WT1 protein-derived peptide, WT1_, : as a HLA-A^*0206-restricted, WT1-specific CTL epitope
- BAFF-R is Expressed on B-cell Lymphomas Depending on their Origin, and its Related to Proliferation Index of Nodal Diffuse Large B-cell Lymphomas
- A WT1 protein-derived, naturally processed 16-mer peptide, WT1_, is a promiscuous helper peptide for induction of WT1-specific Th1-type CD4^+ T cells
- STM Study of Anisotropic Superconducting Gap of Bi_2Sr_2CaCu_2O_8
- Direct Observation of d-Wave Superconducting Gap in κ-(BEDT-TTF)_2Cu[N(CN)_2]Br with Scanning Tunneling Microscopy(Condensed matter: electronic structure and electrical, magnetic, and optical properties)
- Comparison of Long-Term Clinical Outcomes of CHOP Chemotherapy between Japanese Patients with Nodal Peripheral T-Cell Lymphomas and Those with Diffuse Large B-Cell Lymphoma in the Study Group of the Tohoku Hematology Forum
- Bilateral Conjunctival Lesions in Blastic Plasmacytoid Dendritic Cell Neoplasm
- Clinicopathological Features of Malignant Lymphoma in Japan : The Miyagi Study
- Relevance of monitoring metabolic reduction in patients with relapsed or refractory follicular and mantle cell lymphoma receiving bendamustine : a multicenter study
- Lack of non-hematological cross intolerance of dasatinib to imatinib in imatinib-intolerant patients with Philadelphia chromosome positive chronic myeloid leukemia or acute lymphatic leukemia : a retrospective safety analysis
- Direct antiglobulin test-negative autoimmune hemolytic anemia associated with HLA-haploidentical stem cell transplantation
- Use of mycophenolate mofetil in patients received allogeneic hematopoietic stem cell transplantation in Japan
- Successful treatment with nilotinib after imatinib failure in a CML patient with a four-way Ph chromosome translocation and point mutations in BCR/ABL gene
- Neurotoxins, 1-methy1-4-phenyl-1, 2, 3, 6-tetrahydropyridine, 1, 2, 3, 4, -tetrahydroisoquinoline, N-methyl-tetrahydroisoquinoline and 1-benzyl-tetrahydroisoquinoline, are substrates for rat liver flavin-containing monooxygenase(FMO) expressed in yeast
- Rituximab monotherapy with eight weekly infusions for relapsed or refractory patients with indolent B cell non-Hodgkin lymphoma mostly pretreated with rituximab : A multicenter phase II study
- Local Recurrence as Immunoglobulin G4 (IgG4)-Related Disease 10 Years after Radiotherapy to Ocular Adnexal Extranodal Marginal Zone B-Cell Lymphoma of Mucosa-Associated Lymphoid Tissue
- Strategy for bone marrow transplantation in eculizumab-treated paroxysmal nocturnal hemoglobinuria
- Diagnosis of Intestinal Graft-versus-Host Disease and Thrombotic Microangiopathy after Allogeneic Stem Cell Transplantation
- Orbital MALT Lymphoma, Abdominal Hodgkin lymphoma, and Systemic Diffuse Large B-cell Lymphoma Develop Sequentially in One Patient
- Histological and immunohistochemical features of gingival enlargement in a patient with AML
- Feasibility of unmanipulated haploidentical stem cell transplantation using standard GVHD prophylaxis for HLA-homozygous patients
- Phase II study of cyclophosphamide, doxorubicin, vincristine, prednisolone (CHOP) therapy for newly diagnosed patients with low-and low-intermediate risk, aggressive non-Hodgkin's lymphoma : final results of the Japan Clinical Oncology Group Study, JCOG95
- Surgical Resection of a Massive Primary Mediastinal Liposarcoma Using Clamshell Incision Combined with Lower Median Sternotomy: Report of a Case
- Adult Mesenchymal Hamartoma of the Chest Wall: Report of a Case
- Germinal center B-cell-like diffuse large B-cell lymphoma of the duodenum is associated with t(14 ; 18) translocation