Morphological spectrum of cyclin D1-positive mantle cell lymphoma : Study of 168 cases
スポンサーリンク
概要
- 論文の詳細を見る
- 2001-10-01
著者
-
UIKE Naokuni
Department of Hematology, National Kyushu Cancer Center
-
MATSUNO Yoshihiro
Department of Surgical Pathology, Hokkaido University Hospital
-
MORISHIMA Yasuo
Department of Hematology and Cell Therapy, Aichi Cancer Center
-
Tobinai K
Hematology And Stem Cell Transplantation Divisions National Cancer Center Hospital
-
Tobinai Kensei
国立がんセンター中央病院 血液内科グループ
-
Tobinai Kensei
東海大学 医学部
-
MIZOGUCHI Yoshikazu
Departments of Pathology, Fujita Health University School of Medicine
-
NAKAMURA Shigeo
Department of Clinical Pathology, Aichi Cancer Center Hospital
-
KOJIMA Masaru
Department of Anatomic and Diagnostic Pathology, Dokkyo University School of Medicine
-
Nakamura Shigeo
群馬県立がんセンター 病理検査
-
SETO Masao
Laboratories of Chemotherapy and Immunology, Aichi Cancer Research Institute
-
Maeda S
Center For Hematopoietic Disorders Ohta Nishinouchi Hospital The Ohta Foundation
-
Seto M
Department Of Hematology And Chemotherapy
-
YATABE Yasushi
Department of Pathology and Molecular Diagnosis, Aichi Cancer Center Central Hospital
-
Kojima M
Department Of Anatomic And Diagnostic Pathology Dokkyo University School Of Medicine
-
Usubuchi Noriko
国立がんセンター中央病院
-
Usubuchi Noriko
Hematology And Oncology Division National Cancer Center Hospital East
-
Tanimoto Kazuki
国立がんセンター中央病院
-
Uike Naokuni
Department Of Hematology National Kyushu Cancer Center Hospital
-
Itoh K
Division Of Oncology And Hematology National Cancer Center Hospital East
-
Uoshima Nobuhiko
京都府立医科大学 血液・腫瘍内科学
-
Uoshima Nobuhiko
1st Department Of Internal Medicine Kyoto Prefectureal University Of Medicine
-
Miyawaki Shuichi
Leukemia Research Center Saiseikai Maebashi Hospital
-
Usui Noriko
東京慈恵会医科大学附属病院 中央検査部
-
Usui N
Division Of Hematology And Oncology Department Of Medicine Jikei University
-
Usui Noriko
Jikei University Hospital
-
Ichimura Koichi
Department Of Hematology And Rheumatology Tohoku University Graduate School Of Medicine
-
Ishizawa Kenichi
東北大学 血液・免疫病学分野
-
Ishizawa Kenichi
国立がんセンター東病院
-
OGITA Masami
Sapporo National Hospital
-
Tsubaki Kazuo
浜松医科大学 第3内科
-
Suzuki R
Department Of Hsct Data Management Nagoya University Hospital
-
Suzuki Ritsurou
東京大学医学部附属病院 無菌治療部
-
Suzuki Ritsuro
豊橋市民病院 血液・腫瘍内科
-
YAMAGUCHI Motoko
Second Department of Internal Medicine, Mie University School of Medicine
-
SUZUKI Ritsuro
Laboratory of Chemotherapy, Aichi Cancer Center Institute
-
Matsumoto-mishima Yuko
癌研究会癌化学療法センター 臨床研究部
-
Takeuchi Kengo
Cancer Inst. Hospital Tokyo Jpn
-
Kume M
Department Of Hematology Sapporo Hokuyu Hospital
-
Sakai Mari
Department Of Hematology And Molecular Medicine Unit Atomic Bomb Disease Institute Nagasaki Universi
-
Matsuno Y
Department Of Surgical Pathology Hokkaido University Hospital
-
Matsuno Yoshihiro
Department Of Chemotherapy Tokyo Metropolitan Cancer And Infectious Diseases Center Komagome Hospita
-
OKAMOTO Masataka
Department of Internal Medicine, Fujita Health University School of Medicine
-
Nakamura S
Department Of Pathology And Clinical Laboratories Nagoya University Hospital
-
Nakamura Shigeo
Department Of Pathology Nagoya University School Of Medicine
-
Kasai M
Department Of Anatomic And Diagnostic Pathology Dokkyo University School Of Medicine
-
TOBINAI Kensei
Department of Pharmacotherapy, National Cancer Institute
-
ICHINOHAZAMA Ryo
Department of Oral Pathology, Tohoku University School of Dentistry
-
TAMARU Jun-ichi
Department of Pathology, Saitama Medical Center, Saitama Medical School
-
HASHIMOTO Yuko
First Department of Pathology, Fukushima Medical College
-
ISODA Kotaro
Department of Pathology, Minami-Ohsaka General Hospital
-
SUCHI Taizan
Department of Pathology and Clinical Laboratories, Aichi Cancer Center Hospital
-
Sato M
Division Of Molecular Medicine Aichi Cancer Center Research Institute
-
Sano Masayuki
Niigata Cancer Center Hospital
-
Seto Masao
Laboratory Of Chemotherapy Aichi Cancer Center Research Institute
-
Suchi Taizan
Department Of Pathology And Clinical Laboratories Aichi Cancer Center Hospital
-
Suchi Taizan
Department Of Clinical Laboratories Aichi Cancer Center Hospital
-
Isoda Kotaro
Department Of Pathology Minami-ohsaka General Hospital
-
Tamaru Jun-ichi
Department Of Pathology Saitama Medical Center
-
Tamaru Jun-ichi
Department Of Pathology Saitama Medical Center Saitama Medical School
-
Kato M
Department Of Internal Medicine & Molecular Science Nagoya City University Graduate School Of Me
-
Yatabe Yasushi
Department Of Pathology Aichi Cancer Center
-
Yatabe Yasushi
Department Of Pathology And Molecular Diagnostics Aichi Cancer Center Research Institute
-
Yatabe Y
Aichi Cancer Center Hospital
-
Nakamura Shigeo
Department Of Pathology Nagoya University Graduate School Of Medicine
-
Uike Naokuni
Department Of Hemato-oncology Kyushu Cancer Center
-
Yamamoto Masahiko
Department Of Pediatrics Nagoya City University Medical School
-
Shamoto M
Fujita Health Univ. Toyoake Jpn
-
Kojima Masaru
Department Of Anatomic And Diagnostic Pathology Dokkyo University School Of Medicine
-
Minami S
Nagasaki Cml Study Group
-
Tobinai K
National Cancer Center Hospital Tokyo Jpn
-
Seto Masao
Laboratories Of Chemotherapy And Immunology Aichi Cancer Research Institute
-
Matsuno Yoshihiro
Department Of Cell Biology Tokai University School Of Medicine
-
Ichimura Koichi
Department Of Pathology Okayama University Graduate School Of Medicine Dentistry And Pharmaceutical
-
Matsuda Shin
Center For Hematopoietic Disorders Ohta Nishinouchi Hospital The Ohta Foundation
-
Suzuki Ritsurou
Department Of Hematology And Chemotherapy Aichi Cancer Center
-
Suzuki Ritsuro
Laboratory Of Chemotherapy Aichi Cancer Center Institute
-
Miura Shigeto
Department Of Breast Surgery Aichi Cancer Center Hospital
-
Morishima Yasuo
Department Of Hematology And Chemotherapy
-
Miyawaki Shuichi
Saiseikai Maebashi Hospital Maebashi Jpn
-
Takatsuki K
Kumamoto Univ. School Of Medicine Kumamoto Jpn
-
Kami Masahiro
Division Of Hematology/oncology Kameda General Hospital
-
Yatabe Yasushi
Department Of Ophthalmology And Pathology Nagoya University School Of Medicine
-
Kasai Masanobu
First Department Of Internal Medicine Nagoya University School Of Medicine
-
Kawase Takakazu
医学生物学研究所
-
Tobinai Kensei
National Cancer Center Hospital
-
Tobinai Kensei
Department Of Pharmacotherapy National Cancer Institute
-
Ichimura Koichi
Department Of Pathology Okayama University Graduate School Of Medicine And Dentistry
-
Yamamoto Masahiko
Mie University Graduate School Of Medicine
-
Yamaguchi M
Mie Univ. School Of Medicine Mie
-
Ichimura Koichi
Department Of Pathology And Molecular Diagnostics Aichi Cancer Center
-
Ichimura Kouichi
Department Of Pathology Okayama University Medical School And Graduate School Of Medicine Dentistry
-
Okamoto Masataka
Department Of Medicine Fujita-health University School Of Medicine
-
Okamoto Masataka
Department Of Hematology School Of Medicine Fujita Health University
-
Yatabe Yasushi
Division Of Pathology Aichi Cancer Center Research Institute
-
Morishima Yasuo
Department Of Hematology And Cell Therapy Aichi Cancer Center
-
Takeyama K
National Cancer Center Hospital Tokyo Jpn
-
Yamaguchi Motoko
Second Department Of Internal Medicine Mie University Faculty Of Medicine
-
Usui Noriko
Division Of Oncology & Hematology Department Of Internal Medicine The Jikei University School Of
-
Kojima Masaru
Department Of Anatomic And Diagnostic Pathology Dokkyo Medical University
-
Suzuki Ritsuro
Department Of Hsct Data Management And Biostatistics Nagoya University School Of Medicine
-
Hashimoto Yuko
First Department Of Pathology Fukushima Medical College
-
Ichinohazama Ryo
Department Of Oral Pathology Tohoku University School Of Dentistry
-
Moritaka S
Department Of Surgery Ii Nagoya City University Medical School
-
Mizoguchi Yoshikazu
Department Of Maxillofacial Diagnostic Science Division Of Pathology Kanagawa Dental College
-
Yatabe Yasushi
Department Of Molecular Diagnosis Aichi Cancer Center Hospital
-
Kobayashi Masahide
The Department Of Hematology Hamamatsu West Medical Center
-
Morishima Yasuo
Department Of Pathology And Oncology Institute Of Medical Science University Of Tokyo
-
Okamoto Masataka
Department Of Internal Medicine Division Of Hematology And Medical Oncology Fujita Health University
-
Yatabe Yasushi
Department Of Clinical Laboratory Aichi Cancer Center Hospital
-
Okamoto Masataka
Department Of Internal Medicine Division Of Hematology And Medical Oncology Fujita Health University
-
Tobinai Kensei
Department Of Molecular Medicine And Hematology Molecular Medicine Unit Atomic Bomb Disease Institut
-
Nakamura Shigeo
Department Of Cardiovascular Diseases. Kokura National Hospital
-
Suzuki Risturo
Division Of Molecular Medicine Aichi Cancer Center Research Institute
-
NAKAMURA Shigeo
Department of Applied Chemistry, Faculty of Engineering, Kanagawa University
-
TOBINAI Kensei
Department of Hematology, National Cancer Center Hospital
-
OKAMOTO Masataka
Department of Hematology and Medical Oncology, Fujita Health University School of Medicine
関連論文
- Rituximab in combination with CHOP chemotherapy for the treatment of diffuse large B cell lymphoma in Japan : a retrospective analysis of 1,057 cases from Kyushu Lymphoma Study Group
- Accumulation of common polymorphisms is associated with development of hypertension : a 12-year follow-up from the Ohasama study
- Histological and immunophenotypic changes in 59 cases of B-cell non-Hodgkin's lymphoma after rituximab therapy
- Progressive multifocal leukoencephalopathy in a patient with B-cell lymphoma during rituximab-containing chemotherapy : case report and review of the literature
- Stromal cells in bone marrow play important roles in pro-inflammatory cytokine secretion causing fever following bortezomib administration in patients with multiple myeloma
- Diffuse large B-cell lymphoma after transformation from low-grade follicular lymphoma : morphological, immunohistochemical, and FISH analyses
- Nocardia exalbida brain abscess in a patient with follicular lymphoma
- Phase I and II pharmacokinetic and pharmacodynamic study of the proteasome inhibitor bortezomib in Japanese patients with relapsed or refractory multiple myeloma
- Histological and immunophenotypic changes in 59 cases of B-cell non-Hodgkin's lymphoma after rituximab therapy
- Phase II study of tacrolimus and methotrexate for prophylaxis of acute graft-versus-host disease after HLA-A, B, and DRB1 genotypically mismatched unrelated bone marrow transplantation among Japanese patients
- Promoter Hypermethylation of the DNA-Repair Gene O^6-Methylguanine-DNA Methyltransferase and p53 Mutation in Diffuse Large B-Cell Lymphoma
- Loss of O^6-Methylguanine-DNA Methyltransferase Protein Expression Is a Favorable Prognostic Marker in Diffuse Large B-Cell Lymphoma
- Quantification of molecules in ^1H-NMR metabolomics with formate as a concentration standard
- Standardized Prevalence Ratios for Chronic Hepatitis C Virus Infection Among Adult Japanese Hemodialysis Patients
- In vivo Retrovirus-mediated Herpes Simplex Virus Thymidine Kinase Gene Therapy Approach for Adult T Cell Leukemia in a Rat Model
- Serum Levels of Soluble Fas/APO-1 Receptor in Human Retroviral Infection and Associated Diseases
- Linkage of expression of chemokine receptors (CXCR3 and CCR4) and cytotoxic molecules in peripheral T cell lymphoma, not otherwise specified and ALK-negative anaplastic large cell lymphoma
- Prognostic analysis and a new risk model for Hodgkin lymphoma in Japan
- Dietary Risk Factors for Colon and Rectal Cancers : A Comparative Case-Control Study
- Long-term efficacy of imatinib in a practical setting is correlated with imatinib trough concentration that is influenced by body size : a report by the Nagasaki CML Study Group
- Plasma B-Type Natriuretic Peptide Level and Cardiovascular Events in Chronic Kidney Disease in a Community-Based Population
- Factors Influencing Participation Rate in a Baseline Survey of a Genetic Cohort in Japan
- Epstein-Barr virus involvement is a predictive factor for the resistance to chemoradiotherapy of gastric diffuse large B-cell lymphoma
- Phase I study of radioimmunotherapy with an anti-CD20 murine radioimmunoconjugate (^Y-ibritumomab tiuxetan) in relapsed or refractory indolent B-cell lymphoma
- Durable Response but Prolonged Cytopenia after Cladribine Treatment in Relapsed Patients with Indolent non-Hodgkin's Lymphomas : Results of a Japanese Phase II Study
- t(11 ; 18)-Bearing Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma Responding to Cladribine
- Two Entities of Precursor T-Cell Lymphoblastic Leukemia/Lymphoma Based on Radiologic and Immunophenotypic Findings
- Primary Mediastinal Large B-Cell Lymphoma : A Single-Institution Clinical Study in Japan
- EBV-Positive Burkitt Lymphoma as a Late-Onset Posttransplantion Lymphoproliferative Disorder after Allogeneic Stem Cell Transplantation
- Successful Allogeneic Bone Marrow Transplantation in a Case of Adult Precursor B-Lymphoblastic Lymphoma
- Phase 1/2 clinical study of dasatinib in Japanese patients with chronic myeloid leukemia or Philadelphia chromosome-positive acute lymphoblastic leukemia
- Unrelated-Donor Bone Marrow Transplantation with a Conditioning Regimen Including Fludarabine, Busulfan, and 4 Gy Total Body Irradiation
- Japanese phase II study of ^Y-ibritumomab tiuxetan in patients with relapsed or refractory indolent B-cell lymphoma
- Phase I/II study of humanized anti-CD33 antibody conjugated with calicheamicin, gemtuzumab ozogamicin, in relapsed or refractory acute myeloid leukemia : final results of Japanese multicenter cooperative study
- Evaluation of organ involvement in intravascular large B-cell lymphoma by ^F-fluorodeoxyglucose positron emission tomography
- Sustained Remission after Rituximab-containing Chemotherapy for Intravascular Large B-cell Lymphoma
- Epigenetic Regulation of CD20 Protein Expression in a Novel B-Cell Lymphoma Cell Line, RRBL1, Established from a Patient Treated Repeatedly with Rituximab-Containing Chemotherapy
- Phase III study to evaluate the use of high-dose chemotherapy as consolidation of treatment for high-risk postoperative breast cancer : Japan Clinical Oncology Group study, JCOG 9208
- Phase II Study of Cladribine(2-Chlorodeoxyadenosine) in Relapsed or Refractory Adult T-Cell Leukemia-Lymphoma
- Therapy-Related Leukemia and Myelodysplastic Syndrome: A Large-scale Japanese Study of Clinical and Cytogenetic Features as Well as Prognostic Factors
- Imatinib Provides Durable Molecular and Cytogenetic Responses in a Practical Setting for Both Newly Diagnosed and Previously Treated Chronic Myelogenous Leukemia : A Study in Nagasaki Prefecture, Japan
- Phase II study of a salvage regimen using cyclophosphamide, high-dose cytarabine, dexamethasone, etoposide, and rituximab in patients with relapsed or refractory B-cell non-Hodgkin's lymphoma
- Primary Hepatic Follicular Lymphoma : A Case Report and Discussion of Chemotherapy and Favorable Outcomes
- Characterization of target genes at the 2p15-16 amplicon in diffuse large B-cell lymphoma
- Randomized phase II study of concurrent and sequential rituximab and CHOP chemotherapy in untreated indolent B-cell lymphoma
- Senile Epstein-Barr Virus-Associated B-Cell Lymphoproliferative Disorders : a Mini Review
- CD56/NCAM-Positive Langerhans Cell Sarcoma : A Clinicopathologic Study of 4 Cases
- Phenotypic analysis of peripheral T/NK cell lymphoma : Study of 408 Japanese cases with special reference to their anatomical sites
- Pilot Phase I/II Study of New Salvage Therapy(CHASE) for Refractory or Relapsed Malignant Lymphoma
- Efficacy and Safety of Imatinib Mesylate for Patients in the First Chronic Phase of Chronic Myeloid Leukemia : Results of a Japanese Phase II Clinical Study
- Central nervous system involvement in intravascular large B-cell lymphoma : A retrospective analysis of 109 patients
- Prognostic Significance of CD7^+CD56^+ Phenotype and Chromosome 5 Abnormalities for Acute Myeloid Leukemia M0
- Morphological spectrum of cyclin D1-positive mantle cell lymphoma : Study of 168 cases
- Current Status of Hematopoietic Cell Transplantation for Adult Patients with Hematologic Diseases and Solid Tumors in Japan
- Systemic Mastocytosis with Extensive Polypoid Lesions in the Intestines; Successful Treatment with Interferon-α
- Expression of Human Tumor-Associated Antigen RCAS1 in Adult T-Cell Leukemia/Lymphoma
- Iron Intake and Associated Factors in General Japanese Population : NIPPON DATA80, NIPPON DATA90 and National Nutrition Monitoring
- Melanocytic medulloblastoma with ganglioneurocytomatous differentiation : A case report
- 1P345 NMRメタボロミクスの医療への応用 : 透析患者血漿と廃液の解析(その他,第48回日本生物物理学会年会)
- CHANGES IN ACTIVITIES OF DAILY LIVING,PHYSICAL FITNESS, AND DEPRESSIVE SYMPTOMS AFTER SIX-MONTH PERIODIC WELL-ROUNDED EXERCISE PROGRAMS FOR OLDER ADULTS LIVING IN NURSING HOMES OR SPECIAL NURSING FACILITIES
- Effective and Safe Interferon Treatment for Japanese Patients With Chronic Myelogenous Leukemia Relapse After Bone Marrow Transplantation
- Comparison of genetic aberrations in CD10^+ diffused large B-cell lymphoma and follicular lymphoma by comparative genomic hybridization and tissue-fluorescence in situ hybridization
- MUM1/IRF4 Expression Is an Unfavorable Prognostic Factor in B-Cell Chronic Lymphocytic Leukemia(CLL)/Small Lymphocytic Lymphoma(SLL)
- CD34^+-Selected Autologous Peripheral Blood Stem Cell Transplantation Conditioned With Total Body Irradiation for Malignant Lymphoma: Increased Risk of Infectious Complications
- Assessment of Prognostic Factors in Follicular Lymphoma Patients
- Infrequent BCL10 Mutations in B-Cell Non-Hodgkin's Lymphomas
- Blast crisis of chronic myelogenous leukemia exhibiting immunophenotypic features of a myeloid/natural killer cell precursor
- A high dose chemoradiotherapy and peripheral blood stem cell support combined with the CD34^+-selection method in cyclin D1^+-mantle cell lymphoma
- Somatic Hypermutations in the V_H Segment of Immunoglobulin Genes of CD5-positive Diffuse Large B-Cell Lymphomas
- Role of lymph node density in predicting survival of patients with lymph node metastases after radical cystectomy : A multi-institutional study
- Safety and efficacy of rasburicase (SR29142) in a Japanese phase II study
- Adult T-Cell Leukemia-Lymphoma Successfully Treated with 2-Chlorodeoxyadenosine
- Combination Chemotherapy With Risk Factor-Adjusted Dose Attenuation for High-Risk Myelodysplastic Syndrome and Resulting Leukemia in the Multicenter Study of the Japan Adult Leukemia Study Group (JALSG): Results of an Interim Analysis
- Re-Treatment of Relapsed Indolent B-Cell Lymphoma With Rituximab
- Oncogene Associated cDNA Microarray Analysis Shows PRAME Gene Expression is a Marker for Response to Anthracycline Containing Chemotherapy in Patients with Diffuse Large B-cell Lymphoma
- Long-term Follow-up of 14 Patients with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia following Autologous Bone Marrow Transplantation in First Complete Remission
- A new marrow T cell depletion method using anti-CD6 monoclonal antibody-conjugated magnetic beads and its clinical application for prevention of acute graft-vs.-host disease in allogeneic bone marrow transplantation: results of a phase I-II trial
- Quality of Life in Adult Patients After Stem Cell Transplantation
- Cytotoxic large T-cell lymphoma with fulminant clinical course,CD8^+ and CD56^-phenotype, and its relation to Epstein-Barr virus:a report of two cases
- Quality of Life in Adult Patients after Bone Marrow Transplantation
- Serum thrombopoietin level after allogeneic bone marrow transplantation: possible correlations with platelet recovery, acute graft-versus-host disease and hepatic veno-occlusive disease
- Twenty Years' Experience in Allogeneic Hematopoietic Stem Cell Transplantation for Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia in the Nagoya Blood and Marrow Transplantation Group
- Allogeneic Stem Cell Transplantation for Adult T-Cell Leukemia/Lymphoma
- Epstein-Barr virus nuclear antigen 1-specific CD4^+ T cells directly kill Epstein-Barr virus-carrying natural killer and T cells
- Aberrant expression of BCL2A1-restricted minor histocompatibility antigens in melanoma cells : application for allogeneic transplantation
- Minor histocompatibility antigens as targets for immunotherapy using allogeneic immune reactions
- Growth Inhibition of CD20-positive B Lymphoma Cell Lines by IDEC-C2B8 Anti-CD20 Monoclonal Antibody
- Retrospective Study on the Impact of Hepatitis B and Hepatitis C virus Infection on Hematopoietic Stem Cell Transplantation in Japan
- Monitoring Minimal Residual Disease in Patients With MLL-AF6 Fusion Transcript-Positive Acute Myeloid leukemia Fllowing Allogeneic Bone Marrow Transplantation
- Development of novel humanized anti-CD20 antibodies based on affinity constant and epitope
- Potential efficacy of the oral histone deacetylase inhibitor vorinostat in a phase I trial in follicular and mantle cell lymphoma
- Prognostic impact of immunohistochemical biomarkers in diffuse large B-cell lymphoma in the rituximab era
- Phase II study of oral fludarabine in combination with rituximab for relapsed indolent B-cell non-Hodgkin lymphoma
- Phase I/II and pharmacokinetic study of cladribine with 2-h infusion in Japanese patients with relapsed indolent B-cell lymphoma mostly pretreated with rituximab
- Early treatment of CMV antigenemia with ganciclovir for prevention of fatal CMV disease in patients receiving marrow from HLA-matched unrelated donors
- Follicular dendritic cell sarcoma of small intestine with aberrant T-cell marker expression
- Phase I study of the oral mammalian target of rapamycin inhibitor everolimus (RAD001) in Japanese patients with relapsed or refractory non-Hodgkin lymphoma
- Randomized phase II study of concurrent and sequential combinations of rituximab plus CHOP (cyclophosphamide, doxorubicin, vincristine and prednisolone) chemotherapy in untreated indolent B-cell non-Hodgkin lymphoma : 7-year follow-up results
- Multicenter phase II study of bendamustine for relapsed or refractory indolent B-cell non-Hodgkin lymphoma and mantle cell lymphoma
- Use of tissue microarrays and immunohistochemistry to standardize the diagnosis of gastrointestinal stromal tumors