ELEVATION OF HETEROPHILIC ANTIBODIES TO RABBIT ERYTHROCYTES IN HUMAN PATHOLOGIC SERA : QUANTITATIVE STUDIES BY ELISA USING A GLYCOSPHINGOLIPID ANTIGEN

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概要

• 論文の詳細を見る

• Human heterophilic hemagglutinin to rabbit erythrocytes was quantitatively determined by the hemagglutination test and enzyme linked immunosorbent assay (ELISA) using rabbit erythrocyte pentaglycosyl ceramide (CPH), Gal (α 1-3) Gal (β 1-4) GlcNAc (β 1-3) Gal (β 1-4) Glc-Cer as the antigen. The antibody levels in sera from 74 Hanganutziu-Deicher (H-D) antibody-positive patients were significantly higher than those in sera from 55 healthy donors, and the correlation between the antibody levels detected by ELISA and hemagglutinin titers was significant. The antibody levels detected by ELISA correlated to the IgG antibody levels, while the hemagglutinin titers correlated to the IgM antibody levels. These results suggested that IgG levels as well as IgM levels against rabbit erythrocytes were elevated in H-D antibody-positive patients with various tumors and infectious diseases. In 4 out of 67 cancer patients collected randomly, abnormally high levels of anti-CPH IgG antibody were detected.

• 北海道大学の論文
• 1987-01-30

著者

• Suzuki Eiji

  Department of Internal Medicine II, Fukushima Medical University School of Medicine, Fukushima

• Suzuki E

  Shinshu Univ. Ueda Jpn

• Naiki M

  National Inst. Health Tokyo Jpn

• NAIKI Masaharu

  Department of Veterinary Science, National Institute of Health

• SUZUKI Eiji

  TDK Corporation

• Suzuki Eiji

  Department Of Fine Materials Engineering Faculty Of Textile Science & Technology Shinshu Univers

• Naiki M

  Department Of Veterinary Science

• Naiki Masaharu

  Department Of Biochemistry Faculty Of Veterinary Medicine Hokkaido University:(present Address) Depa

• MUKURIA Chege

  Department Veteriary Science, National Institute of Health

• Mukuria C

  National Inst. Health Tokyo

• Mukuria Chege

  Department Veteriary Science National Institute Of Health

• Suzuki E

  Tdk Corporation

• KUROSAWA Tsutomu

  First Department of Surgery, Tokyo University School of Medicine

• HANAUE Jin

  First Department of Surgery, Tokyo University School of Medicine

• Hanaue Jin

  First Department Of Surgery Tokyo University School Of Medicine

• Kurosawa T

  Inst. Of Experimental Animal Sciences Osaka Univ. Medical School

• Suzuki Eiji

  Department Of Breast Surgery Tokyo Metropolitan Komagome Hospital

• Suzuki Eiji

  Department Of Biochemistry Faculy Of Veterinary Medicine Hokkaido University

• MUKURIA Chege

  Department of Biochemistry, Faculty of Veterinary Medicine, Hokkaido University

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