<原著>過去10年間における低IgA血症について

概要

論文の詳細を見る
In this study, we investigated 202 patients with hypogammaglobulinemia A, in whom blood IgA levels were 50 mg/dl or less, out of a total 29,302 patients examined between January 1978 and July 1988. The incidence of hypogammaglobulinemia was 0.689% of the total cases, and selective IgA deficiency with an IgA level of 10 mg/dl or less was seen in 25 cases (0.085%). Diseases of the hematopoietic system, such as malignant lymphoma, lymphocytic leukemia and lymphadenitis, were the most common underlying diseases. In cases of selective decrease of IgA alone, chronic recurrent infection, such as in bronchial diseases and nephritis were frequently observed. Selective deficiency occurred at a high incidence in association with allergic diseases, nervous diseases, and hepatic diseases. Analysis of lymphocyte subsets in 4 patients with selective IgA deficiency, revealed 3 with decreased CD4+, suggesting reduced in immunological competence.
近畿大学の論文
1990-12-25