<原著>血清浸透圧と血液化学成分

概要

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Determination of serum osmolarity is useful to find out the abnormality of body fluid. Variation in osmolarity of human beings usually remains within 1-2%, whereas various diseases, for instance, renal disease, diabetes mellitus, dehydration, and diabetes insipidus, bring about abnormality in serum osmolarity. The investigation described here was carried out in order to clarify the relationship between serum osmolarity and the composition of the body fluid. The samples were divided according to serum osmolarity into the following three groups. I ; hypoosmolar state 275 mosm/kg H_2O>, II ; normoosmolar state 275-300 mOsm/kg H_2O, III ; hyperosmolar state 300 mOsm/kgH_2O<. Group I exhibited lower values of Na, Ca, and Cl. As for group III, BUN, glucose, Ca, and K showed higher values. Na showed a low value also in 11.9% of hyperosmolar state ; Pseudo-hyponatremia was considered. There was a high correlation between determined values and calculated ones (r=0.935). However, in hyperosmolar state discrepancy between the values came to be noticed, which may be due to the effects of lactic acid, acetone, and potassium. Examination of the blood of postmortem dissection simultaneously performed disclosed markedly elevated values of inorganic phosphorus, potassium, magnesium, CPK, and LDH, in marked hyperosmolarity.
近畿大学の論文
1978-09-25