<原著>気道過敏性に関する研究 : 健常者, 気管支喘息およびその他の呼吸器疾患におけるAstographの比較

概要

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The bronchial hypersensitivity was investigated in 10 healthy subjects, 24 patients with bronchial asthma, 7 patients with chronic bronchitis and 10 patients with other respiratory diseases for a total of 51 cases. The analysis of the change of respiratory resistence curve by Astograph was made on five indicators of Rrs. cont., D min, St, Sr, and Rrs. e. The results obtained are as follows. 1. In the group of nonsmoking, in any case the change in respiratory resistance curve to aerosol methacholine was found. All of the five cases in smoking group showed the change of respiratory resistance curve in methacholine inhalation. The difference of bronchial reactivity was observed between the nonsmoking and the smoking group in healthy subjects as to the D min, St, and Sr. 2. Rrs. cont. in the patients with bronchial asthma was markedly increased compared with the patients with chronic bronchitis, other respiratory diseases and healthy individuals. The group of bronchial asthma showed low D min, high St and Sr, compaired with the group of other respiratory diseases. 3. The cases with high Rrs. cont. value showed high St level, demonstrating significant correlation between these indicators. The patients with bronchial asthma, showed correlation between Rrs. cont. and Rrs. e.
近畿大学の論文
1981-09-25